ArticleDevelopmental cognitive neuroscience2019
Neurofeedback and neuroplasticity of visual self-processing in depressed and healthy adolescents: A preliminary study.
Article in Developmental cognitive neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Trial
- Real-time functional magnetic resonance imaging neurofeedback training of amygdala upregulation increases affective flexibility in depression.Journal of psychiatry & neuroscience : JPNTrial
- Selective encoding failure of self-face identity in subthreshold depression.Psychological research · 2026Article
- Article
- Development of the Nervous System During Adolescence.Advances in experimental medicine and biology · 2026Review
- Self-Processing Circuits Among Depressed Youth After Amygdala Neurofeedback Cued to the Self-Face.Journal of neuroscience research · 2025Article
- Common and disease-specific patterns of functional connectivity and topology alterations across unipolar and bipolar disorder during depressive episodes: a transdiagnostic study.Translational psychiatry · 2025Article
- Graph theory-driven structural and functional connectivity analyses revealing regulatory mechanisms of brain network in patients with classic trigeminal neuralgia.Brain imaging and behavior · 2025Article
- Neural activity during negative self-evaluation is associated with negative self-concept and depressive symptoms in adolescent girls.Development and psychopathology · 2025Article
- Article
- Aberrant intrinsic hippocampal and orbitofrontal connectivity in drug-naive adolescent patients with major depressive disorder.European child & adolescent psychiatry · 2023Article
- Consumer-Grade Electroencephalogram and Functional Near-Infrared Spectroscopy Neurofeedback Technologies for Mental Health and Wellbeing.Sensors (Basel, Switzerland) · 2023Review
- Hypoactive Visual Cortex, Prefrontal Cortex and Insula during Self-Face Recognition in Adults with First-Episode Major Depressive Disorder.Biomedicines · 2023Article
- Emotional Regulation and Adolescent Concussion: Overview and Role of Neuroimaging.International journal of environmental research and public health · 2023Review
- Social Processing in Eating Disorders: Neuroimaging Paradigms and Research Domain Organizational Constructs.Current psychiatry reports · 2022Review
- Self-Enhancement and the Medial Prefrontal Cortex: The Convergence of Clinical and Experimental Findings.Brain sciences · 2022Review
- Stress-related hippocampus activation mediates the association between polyvictimization and trait anxiety in adolescents.Social cognitive and affective neuroscience · 2022Article
- The Current Evidence Levels for Biofeedback and Neurofeedback Interventions in Treating Depression: A Narrative Review.Neural plasticity · 2021Review
- Amygdala Circuitry During Neurofeedback Training and Symptoms' Change in Adolescents With Varying Depression.Frontiers in behavioral neuroscience · 2020Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
Adolescence is a neuroplastic period for self-processing and emotion regulation transformations, that if derailed, are linked to persistent depression. Neural mechanisms of adolescent self-processing and emotion regulation ought to be targeted via new treatments, given moderate effectiveness of current interventions. Thus, we implemented a novel neurofeedback protocol in adolescents to test the engagement of circuits sub-serving self-processing and emotion regulation.
methodsDepressed (n = 34) and healthy (n = 19) adolescents underwent neurofeedback training using a novel task. They saw their happy face as a cue to recall positive memories and increased displayed amygdala and hippocampus activity. The control condition was counting-backwards while viewing another happy face. A self vs. other face recognition task was administered before and after neurofeedback training.
resultsAdolescents showed higher frontotemporal activity during neurofeedback and higher amygdala and hippocampus and hippocampi activity in time series and region of interest analyses respectively. Before neurofeedback there was higher saliency network engagement for self-face recognition, but that network engagement was lower after neurofeedback. Depressed youth exhibited higher fusiform, inferior parietal lobule and cuneus activity during neurofeedback, but controls appeared to increase amygdala and hippocampus activity faster compared to depressed adolescents.
conclusionsNeurofeedback recruited frontotemporal cortices that support social cognition and emotion regulation. Amygdala and hippocampus engagement via neurofeedback appears to change limbic-frontotemporal networks during self-face recognition. A placebo group or condition and contrasting amygdala and hippocampus, hippocampi or right amygdala versus frontal loci of neurofeedback, e.g. dorsal anterior cingulate cortex, with longer duration of neurofeedback training will elucidate dosage and loci of neurofeedback in adolescents.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.