Evidence map›Paper›PMID 31733461›Full record

ArticleJournal of affective disorders2020

A network perspective on body dysmorphic disorder and major depressive disorder.

Berta J Summers, George Aalbers, Payton J Jones, Richard J McNally, Katharine A Phillips, Sabine Wilhelm

Open access · greenAbstract read
In one paragraph

Article in Journal of affective disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 3 pooled it
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 3 syntheses or guidelines pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Review
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  11. Review
  12. The network structure of schema modes.Clinical psychology & psychotherapy · 2021
    Article
  13. Phenotype Network and Brain Structural Covariance Network of Major Depression.Advances in experimental medicine and biology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Berta J SummersMassachusetts General Hospital, Harvard Medical School, United States. Electronic address: bsummers@mgh.harvard.edu.
George AalbersUniversity of Amsterdam, Netherlands.
Payton J JonesHarvard University, United States.
Richard J McNallyHarvard University, United States.
Katharine A PhillipsNew York-Presbyterian Hospital, Weill Cornell Medical College, United States.
Sabine WilhelmMassachusetts General Hospital, Harvard Medical School, United States.
Harvard University Press · USMassachusetts General Hospital · USNewYork–Presbyterian Hospital · USUniversity of Amsterdam · NL

Funding

Pharmacotherapy Relapse Prevention in BDDR01MH072917 · NIMH · BUTLER HOSPITAL (PROVIDENCE, RI) · PI PHILLIPS, KATHARINE ANNE · 2005 to 2009
$1.5M
Pharmacotherapy Relapse Prevention in Body Dysmorphic DisorderR01MH072854 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI WILHELM, SABINE · 2005 to 2009
$1.5M
CBT Treatment Development for Body Dysmorphic DisorderR34MH070490 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI WILHELM, SABINE · 2004 to 2006
$621k
NIMH NIH HHS R01 MH072854NIMH NIH HHS R01 MH072917NIMH NIH HHS R34 MH070490
6 · The paper itself

Abstract

backgroundBody dysmorphic disorder (BDD) is a highly debilitating mental disorder associated with notable psychosocial impairment and high rates of suicidality. This study investigated BDD from a network perspective, which conceptualizes mental disorders as systems of symptoms that cause and exacerbate one another (e.g., preoccupation with perceived appearance defect triggering compulsive checking in the mirror).

methodsIn a sample of BDD patients (N = 148), we used cross-sectional network models to explore the network structure of 1) BDD symptoms and 2) BDD symptoms and major depressive disorder (MDD) symptoms, and tested which symptoms were most central (i.e., most strongly associated to other symptoms).

resultsInterference in functioning due to appearance-related compulsions (BDD), feelings of worthlessness (MDD), and loss of pleasure (MDD) were most central.

conclusionThese symptoms were most strongly predictive of other BDD and MDD symptoms and may be features of BDD that warrant prioritization in theory development and treatment. A limitation of our study is that the precision of these findings may be limited due to a small sample size relative to the number of parameters. Replication studies in larger samples of BDD patients are needed.

Indexed as

Neural Networks, ComputerAdultBody Dysmorphic DisordersCompulsive BehaviorCross-Sectional StudiesFemaleHumansMajor Depressive DisorderMaleMiddle AgedBody dysmorphic disorderComorbidityMajor depressive disorderNetwork analysis

Identifiers

PMID31733461
PMCPMC6924632
OpenAlexW2986495254

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.