Evidence map›Paper›PMID 31733450›Full record

ArticleAmerican heart journal2020

Age, knowledge, preferences, and risk tolerance for invasive cardiac care.

Michael G Nanna, Eric D Peterson, Angie Wu, Tina Harding, Anthony N Galanos, Lisa Wruck, Karen P Alexander

Open access · greenAbstract read
In one paragraph

Article in American heart journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 33 citations in OpenAlex.

  1. Trial
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  13. Review
  14. Complex Percutaneous Coronary Intervention Outcomes in Older Adults.Journal of the American Heart Association · 2023
    Article
  15. Article
  16. Article
  17. Article
  18. Stable Coronary Artery Disease in the Age of Geriatric Cardiology.Journal of the American College of Cardiology · 2023
    Article
  19. Article
  20. Management of Stable Angina in the Older Adult Population.Circulation. Cardiovascular interventions · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Michael G NannaDuke Clinical Research Institute, Durham, NC. Electronic address: michael.nanna@duke.edu.
Eric D PetersonDuke Clinical Research Institute, Durham, NC.
Angie WuDuke Clinical Research Institute, Durham, NC.
Tina HardingDuke Clinical Research Institute, Durham, NC.
Anthony N GalanosDuke Clinical Research Institute, Durham, NC.
Lisa WruckDuke Clinical Research Institute, Durham, NC.
Karen P AlexanderDuke Clinical Research Institute, Durham, NC.
Clinical Research Institute · US

Funding

Postdoctoral Training in Cardiovascular Clinical ResearchT32HL069749 · NHLBI · DUKE UNIVERSITY · PI MARK, DANIEL B · 2003 to 2023
$6.7M
NHLBI NIH HHS T32 HL069749
6 · The paper itself

Abstract

BACKGROUND/

objectivesThe extent to which individual knowledge, preferences, and priorities explain lower use of invasive cardiac care among older vs. younger adults presenting with acute coronary syndrome (ACS) is unknown. We directly surveyed a group of patients to ascertain their preferences and priorities for invasive cardiovascular care.

designWe performed a prospective cohort study of adults hospitalized with ACS. We surveyed participants regarding their knowledge, preferences, goals, and concerns for cardiac care, as well as their risk tolerance for coronary artery bypass grafting (CABG).

settingSingle academic medical center.

participantsSix hundred twenty-eight participants (373 <75 years old; 255 ≥75 years old). MEASUREMENTS: We compared baseline characteristics, knowledge, priorities, and risk tolerance for care across age strata. We also assessed pairwise differences with 95% confidence intervals (CI) between age groups for key variables of interest.

resultsCompared with younger patients, older participants had less knowledge of invasive care; were less willing to consider cardiac catheterization (difference between 75-84 and< 65 years old: -7.8%, 95% CI: -14.4%,-1.3%; for ≥85 vs. <65: -15.7%, 95% CI: -29.8%,-1.6%), percutaneous coronary intervention (difference between 75-84 and< 65 years old: -12.8%, 95% CI: -20.8%,-4.8%; for ≥85 vs. <65: -24.8%, 95% CI: -41.2%,-8.5%), and CABG (difference between 75-84 and< 65 years old: -19.0%, 95% CI: -28.2%,-9.9%; for ≥85 vs. <65: -39.1%, 95% CI: -56.0%,-22.2%); and were more risk averse for CABG surgery (p < .001), albeit with substantial inter-individual variability and individual outliers. Many patients who stated they were not initially willing to undergo an invasive cardiovascular procedure actually ended up undergoing the procedure (49% for cardiac catheterization and 22% for PCI or CABG).

conclusionAge influences treatment goals and willingness to consider invasive cardiac care, as well as risk tolerance for CABG. Individuals' willingness to undergo invasive cardiovascular procedures loosely corresponds with whether that procedure is performed after discussion with the care team.

Indexed as

Age FactorsHealth Knowledge, Attitudes, PracticePatient PreferenceAcute Coronary SyndromeAgedAged, 80 and overCardiac CatheterizationCoronary Artery BypassGoalsHumansInpatientsMiddle AgedMyocardial RevascularizationProspective StudiesRisk Assessment

Identifiers

PMID31733450
PMCPMC6944066
OpenAlexW2982068123

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.