Evidence map›Paper›PMID 31733290›Full record

ArticleBrain, behavior, and immunity2020

Differential DNA methylation in experienced meditators after an intensive day of mindfulness-based practice: Implications for immune-related pathways.

R Chaix, M Fagny, M Cosin-Tomás, M Alvarez-López, L Lemee, B Regnault, R J Davidson, A Lutz, P Kaliman

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Brain, behavior, and immunity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06583395 (Effects Of Meditation On The Gut Microbiome And Human Health and Disease), which is not on this map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06583395 enrolling by invitationnot on this mapstarted 2021, after this paper: background citation

Effects Of Meditation On The Gut Microbiome And Human Health and Disease

TypeobservationalSponsorTobias Moeller-BertramRan2021 to 2025Enrolled3,000ConditionsAmyotrophic Lateral Sclerosis (ALS), Angina, Stable, Anxiety, AsthmaArmsAdvanced multi-component meditation practice
3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 63 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 9 institutions in 4 countries.

R ChaixUnité d'Eco-anthropologie (EA), Museum National d'Histoire Naturelle, CNRS, Université Paris Diderot, 75016 Paris, France. Electronic address: raphaelle.chaix@mnhn.fr.
M FagnyGénétique Quantitative et Évolution, Evolution - Le Moulon, INRA, Université Paris-Sud, CNRS, AgroParisTech, Université Paris-Saclay, France.
M Cosin-TomásDepartment of Human Genetics, McGill University, Research Institute of the McGill University Health Center, Montreal, Quebec, Canada.
M Alvarez-LópezUnitat de Farmacologia, Facultat de Farmàcia, Institut de Biomedicina, Universitat de Barcelona (IBUB), Nucli Universitari de Pedralbes, Barcelone, Spain.
L LemeePlate-forme de Génotypage des Eucaryotes, Pôle Biomics, Institut Pasteur, Paris, France; Plateforme Biomics, Institut Pasteur, Paris, France.
B RegnaultPlate-forme de Génotypage des Eucaryotes, Pôle Biomics, Institut Pasteur, Paris, France; Biology of Infection Unit, Inserm U1117. Pathogen Discovery Laboratory, Institut Pasteur, Paris, France.
R J DavidsonCenter for Healthy Minds, University of Wisconsin-Madison, USA.
A LutzLyon Neuroscience Research Center, INSERM U1028, CNRS UMR5292, Lyon 1 University, Lyon, France.
P KalimanCenter for Healthy Minds, University of Wisconsin-Madison, USA; Faculty of Health Sciences, Universitat Oberta de Catalunya, Barcelona, Spain. Electronic address: pkaliman@uoc.edu.
Centre National de la Recherche Scientifique · FRInserm · FRInstitut Pasteur · FRMcGill University Health Centre · CAUniversitat de Barcelona · ESUniversitat Oberta de Catalunya · ESUniversité Claude Bernard Lyon 1 · FRUniversité Paris-Sud · FRUniversity of Wisconsin–Madison · US

Funding

Wisconsin Center for the Neuroscience and Psychophysiology of MeditationP01AT004952 · NCCIH · UNIVERSITY OF WISCONSIN-MADISON · PI DAVIDSON, RICHARD J · 2008 to 2018
$14.7M
NCCIH NIH HHS P01 AT004952
6 · The paper itself

Abstract

The human methylome is dynamically influenced by psychological stress. However, its responsiveness to stress management remains underexplored. Meditation practice has been shown to significantly reduce stress level, among other beneficial neurophysiological outcomes. Here, we evaluated the impact of a day of intensive meditation practice (t

Indexed as

MeditationMindfulnessDNA MethylationEpigenomeFemaleHumansLeukocytes, MononuclearLongitudinal StudiesMaleMiddle AgedStress, PsychologicalEpigeneticsMeditationMethylationPeripheral blood mononuclear cells

Identifiers

PMID31733290
PMCPMC7010561
OpenAlexW2983360131

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.