Evidence map›Paper›PMID 31732919›Full record

ArticleJournal of cardiovascular translational research2020

Impact of Free-Breathing Phase-Contrast MRI on Decision-Making in Fontan Surgical Planning.

Zhenglun Alan Wei, Phillip M Trusty, Yingnan Zhang, Elaine Tang, Kevin K Whitehead, Mark A Fogel, Ajit P Yoganathan

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Journal of cardiovascular translational research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
  2. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Zhenglun Alan WeiWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology & Emory University, Technology Enterprise Park, Suite 200, 387 Technology Circle, Atlanta, GA, 30313-2412, USA.
Phillip M TrustyWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology & Emory University, Technology Enterprise Park, Suite 200, 387 Technology Circle, Atlanta, GA, 30313-2412, USA.
Yingnan ZhangWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology & Emory University, Technology Enterprise Park, Suite 200, 387 Technology Circle, Atlanta, GA, 30313-2412, USA.
Elaine TangSchool of Chemical and Biomolecular Engineering, Georgia Institute of Technology, Atlanta, GA, USA.
Kevin K WhiteheadDivision of Cardiology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Mark A FogelDivision of Cardiology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Ajit P YoganathanWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology & Emory University, Technology Enterprise Park, Suite 200, 387 Technology Circle, Atlanta, GA, 30313-2412, USA. ajit.yoganathan@bme.gatech.edu.
Georgia Institute of Technology · USChildren's Hospital of Philadelphia · USThe Wallace H. Coulter Department of Biomedical Engineering · US

Funding

Improving Flow Dynamics in Fontan SurgeriesR01HL067622 · NHLBI · GEORGIA INSTITUTE OF TECHNOLOGY · PI YOGANATHAN, AJIT P · 2002 to 2006
$5.2M
Understanding mechanisms of Fontan failure and key predictors for patient outcomeR01HL098252 · NHLBI · GEORGIA INSTITUTE OF TECHNOLOGY · PI YOGANATHAN, AJIT P · 2010 to 2013
$3.0M
6 · The paper itself

Abstract

Fontan surgical planning ranks proposed surgical options according to their hemodynamics assessed by computational fluid dynamic (CFD) modeling. CFD commonly utilizes blood flow acquired under breath-holding (BH) conditions. Ignoring the free-breathing (FB) effect on blood flow waveforms may impact the ranking of surgical options. This study investigates such a potential impact by including ten Fontan patients who had blood flow acquisitions under both BH and FB conditions. A virtual surgery platform was used to generate two surgical options for each patient: (1) a traditional Fontan conduit and (2) a Y-graft. These options were ranked based on clinically relevant hemodynamic metrics: power loss (PL) and hepatic flow distribution (HFD). No difference was found in the ranking of options between using FB and BH flow acquisitions. The findings indicated that decision-making is not affected by the types of flow acquisition for Fontan surgical planning.

Indexed as

Clinical Decision-MakingDiagnosis, Computer-AssistedFontan ProcedureMagnetic Resonance ImagingPatient-Specific ModelingAdolescentFemaleHeart Defects, CongenitalHemodynamicsHumansMalePatient SelectionPredictive Value of TestsProof of Concept StudyReoperationRespiratory MechanicsComputational fluid dynamicsFontan surgical planningPhase-contrast MRI

Identifiers

PMID31732919
OpenAlexW2987422290

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.