Evidence map›Paper›PMID 31732863›Full record

ArticleProbiotics and antimicrobial proteins2020

Potential Probiotic Lactobacillus rhamnosus (MTCC-5897) Inhibits Escherichia coli Impaired Intestinal Barrier Function by Modulating the Host Tight Junction Gene Response.

Mohd Iqbal Bhat, Kandukuri Sowmya, Suman Kapila, Rajeev Kapila

Abstract read
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Article in Probiotics and antimicrobial proteins, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. International journal of molecular sciences · 2025
    Article
  3. Probiotics and the intestinal tight junction barrier function.Frontiers in cell and developmental biology · 2025
    Review
  4. Frontiers in microbiology · 2025
    Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Frontiers in immunology · 2022
    Article
  12. Article
  13. Review
  14. Article
  15. Effects ofFrontiers in veterinary science · 2021
    Article
  16. Review
  17. Gut microbes
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mohd Iqbal BhatAnimal Biochemistry Division, ICAR-National Dairy Research Institute, Karnal, Haryana, 132001, India.
Kandukuri SowmyaAnimal Biochemistry Division, ICAR-National Dairy Research Institute, Karnal, Haryana, 132001, India.
Suman KapilaAnimal Biochemistry Division, ICAR-National Dairy Research Institute, Karnal, Haryana, 132001, India.
Rajeev KapilaAnimal Biochemistry Division, ICAR-National Dairy Research Institute, Karnal, Haryana, 132001, India. rkapila69@rediffmail.com.ORCID http://orcid.org/0000-0002-2795-3720

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Probiotic as a preventive medicine is emerging as an indispensable tool in addressing the foodborne infections or gastrointestinal disorders. The present study was sought to determine the in vitro prophylactic potential of probiotic Lactobacillus rhamnosus (LR: MTCC-5897) against Escherichia coli (ATCC 14948) induced impairment in intestinal barrier function using Caco-2 cells. Intestinal cells exposed to E. coli demonstrated significantly higher phenol red flux (p < 0.05) and concomitantly decreased TEER (0.69 ± 0.01) in contrast to control or L. rhamnosus (10

Indexed as

AntibiosisLacticaseibacillus rhamnosusProbioticsCaco-2 CellsEscherichia coliHumansPermeabilityIntestinal permeabilityLactobacillus rhamnosusPhenol red fluxTight junctionsTransepithelial electrical resistance

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.