Trial reportEuropean journal of nutrition2020
A single dose of purple grape juice improves physical performance and antioxidant activity in runners: a randomized, crossover, double-blind, placebo study.
Trial report in European journal of nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 22 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Pooled it
- Polyphenol supplementation boosts aerobic endurance in athletes: systematic review.Frontiers in physiology · 2024Pooled it
- Pooled it
- A single dose of cajuína does not improve leukocyte count, lipid peroxidation, and physical performance in runners: a randomized, crossover, double‑blind, placebo study.European journal of nutrition · 2025Trial
- Effects of a Single Oral Megadose of Vitamin D3 on Inflammation and Oxidative Stress Markers in Overweight and Obese Women: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.Diabetes, metabolic syndrome and obesity : targets and therapy · 2021Trial
- Effects of different antioxidants on exercise-induced oxidative stress and muscle damage in athletes: a systematic review and meta-analysis.BMC sports science, medicine & rehabilitation · 2025Article
- Anthocyanin-Rich Purple Plant Foods: Bioavailability, Antioxidant Mechanisms, and Functional Roles in Redox Regulation and Exercise Recovery.Nutrients · 2025Review
- Polyphenol-Rich Snack Consumption during Endurance Exercise Training Improves Nitric Oxide Bioavailability but does not Improve Exercise Performance in Male Cyclists: A Randomised Controlled Trial.Current developments in nutrition · 2025Article
- Dietary polyphenols and human health: sources, biological activities, nutritional and immunological aspects, and bioavailability- a comprehensive review.Frontiers in immunology · 2025Review
- Individual responses to purple grape juice consumption on endurance, explosive power, and fatigue in young male elite soccer players.Frontiers in nutrition · 2025Article
- Almond Consumption Modestly Improves Pain Ratings, Muscle Force Production, and Biochemical Markers of Muscle Damage Following Downhill Running in Mildly Overweight, Middle-Aged Adults: A Randomized, Crossover Trial.Current developments in nutrition · 2024Article
- Polyphenols: Secondary Metabolites with a Biological Impression.Nutrients · 2024Review
- Effect of a cajuína hydroelectrolytic drink on the physical performance and hydration status of recreational runners.Current research in physiology · 2024Article
- The Use of Some Polyphenols in the Modulation of Muscle Damage and Inflammation Induced by Physical Exercise: A Review.Foods (Basel, Switzerland) · 2023Review
- Pure Juice Supplementation: Its Effect on Muscle Recovery and Sports Performance.The Malaysian journal of medical sciences : MJMS · 2023Review
- Physicochemical and functional properties of new sports drink with ricotta cheese whey and a brazilian passion fruit variety.Journal of food science and technology · 2023Article
- Review
- Antioxidative properties of phenolic compounds and their effect on oxidative stress induced by severe physical exercise.The journal of physiological sciences : JPS · 2022Review
- Purple grape juice improves performance of recreational runners, but the effect is genotype dependent: a double blind, randomized, controlled trial.Genes & nutrition · 2022Article
- Contribution of Grape Juice to Develop New Isotonic Drinks With Antioxidant Capacity and Interesting Sensory Properties.Frontiers in nutrition · 2022Review
Corrections and comments
- Erratum issued
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo investigate the effects of a single dose of juice on physical performance, oxidative stress, inflammation and muscle damage in runners.
methodsFourteen recreational male runners (39 ± 9 years, VO
resultsThe participants ran for an average of 59.2 ± 27.8 min until exhaustion in the placebo group and for 68.4 ± 29.7 min until exhaustion in the grape juice intake group, which was a significantly longer time (p = 0.008). This improvement in physical performance was accompanied by a 43.6% increase in TAC (p = 0.000) at the post-exercise timepoint compared to the level at baseline. MDA, A1GPA, hs-CRP, CK, and LDH did not exhibit changes. In contrast, no significant change in any variable was observed after consuming the placebo drink.
conclusionThe single-dose intake of purple grape juice demonstrated an ergogenic effect in recreational runners by increasing run time to exhaustion and increasing antioxidant activity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.