ArticleMikrochimica acta2019
Highly active G-quadruplex/hemin DNAzyme for sensitive colorimetric determination of lead(II).
Article in Mikrochimica acta, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Lipopolysaccharide-Specific Aptasensor: A Spectroscopic Approach for Identifying Gram-Negative Bacteria.Analytical science advances · 2026Article
- Review
- Kinetic analysis of catalytic activity of G-quadruplex/hemin DNAzyme with flanking adenine nucleotides.Scientific reports · 2025Article
- Electrochemiluminescence/Electrochemistry Dual-Mode Synchronous Sensing of PbMolecules (Basel, Switzerland) · 2025Article
- RNA extraction-free workflow integrated with a single-tube CRISPR-Cas-based colorimetric assay for rapid SARS-CoV-2 detection in different environmental matrices.Journal of hazardous materials · 2023Article
- Colorimetric Sensors for Chemical and Biological Sensing Applications.Sensors (Basel, Switzerland) · 2023Review
- Signal-enhanced visual strand exchange amplification detection of African swine fever virus by the introduction of multimeric G-quadruplex/hemin DNAzyme.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2022Article
- Biosensing with DNAzymes.Chemical Society reviews · 2021Review
- Highly Sensitive and Selective Fluorescence "Turn-On" Detection of Pb (II) Based on FeMolecules (Basel, Switzerland) · 2021Article
- Article
- The noncovalent dimerization of a G-quadruplex/hemin DNAzyme improves its biocatalytic properties.Chemical science · 2020Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
A UV-vis, CD, and differential pulse voltammetric study was performed on the deactivation of the activity of parallel G-quadruplex/hemin DNAzymes (G4 DNAzymes) by Pb(II). The G4 DNAzyme carries a d[TC] sequence at its 3' end and is stabilized by potassium(I). On addition of Pb(II), the K(I) ions in the parallel G4 are replaced by Pb(II) to keep the parallel topology. Intruded Pb(II) decrease the affinity between the topology and hemin, this leads to a decrease of DNAzyme activity for catalyzing the oxidation of 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) by hydrogen peroxide to form a green dye with an absorption maximum at 420 nm. The assay does not use any amplification, and has a linear response in the 0.01 to 10 μM Pb(II) concentration range and a 7.1 nM limit of detection. The method was successfully applied to the analysis of spiked water samples. Graphical abstractSchematic diagram of the colorimetric lead(II) assay based on the competition between K
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