ReviewNature reviews. Urology2019
The seminal microbiome in health and disease.
Review in Nature reviews. Urology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04784260 (Microbiome Influence on Seminal Quality on Semen Donors), which is not on this map. Cited by 86 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Microbiome Influence on Seminal Quality on Semen Donors
Who cites it
86 citing papers in PubMed, 3 syntheses or guidelines pooled it, 189 citations in OpenAlex.
- [Advances in the Application of Forensic Microbiome Analysis in Tissue Source Inference].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2025Pooled it
- Potential causes and associated conditions with anti-sperm antibody production among infertile males: a systematic literature review.BMC immunology · 2025Pooled it
- Microbiota and seminal quality: A systematic review.JBRA assisted reproduction · 2023Pooled it
- The impact of probiotics on testosterone synthesis in the TM3 cell line.Clinical and experimental reproductive medicine · 2026Article
- The Female Reproductive Microbiome: Mechanistic Insights and Bioengineering Perspectives.Biology · 2026Review
- Maternal and infant gut microbiome.iMeta · 2026Review
- Unfolding the Semen Microbiota: Implications for Male Infertility.Biomedicines · 2026Review
- Precision culturomics enabled by unlabeled single-cell morphology and Raman spectra.Nature communications · 2026Article
- Interplay of Microbiome, Oxidative Stress and Inflammation in Health and Disease.Antioxidants (Basel, Switzerland) · 2026Review
- Decoding the reproductive microbiome: enabling clinical and biological insights through machine and deep learning.Frontiers in endocrinology · 2026Review
- Decoding the seminal microbial fingerprint and semen quality: insights from the first Greek pilot study.Frontiers in microbiology · 2026Article
- The impact of vasectomy on the seminal microbiome: possible implications and source of microbes.Human reproduction open · 2026Article
- Evaluation of the semen microbiome for fertility in men with obesity using next-generation sequencing.Basic and clinical andrology · 2025Article
- Article
- Research trend on the emerging role of the microbiome in idiopathic male infertility.Antonie van Leeuwenhoek · 2025Review
- Natural sex reversal imparts permanent compositional changes to the swamp eel gonadal microbiome.Microbiome · 2025Article
- Beyond Genes: Mechanistic and Epidemiological Insights into Paternal Environmental Influence on Offspring Health.Current environmental health reports · 2025Review
- Article
- Lifestyle and Environmental Factors Affecting Male Fertility, Individual Predisposition, Prevention, and Intervention.International journal of molecular sciences · 2025Review
- Unlocking the Interactions Between the Whole-Body Microbiome and HPV Infection: A Literature Review.Pathogens (Basel, Switzerland) · 2025Review
26 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Owing to the fact that there are more microbial than human cells in our body and that humans contain more microbial than human genes, the microbiome has huge potential to influence human physiology, both in health and in disease. The use of next-generation sequencing technologies has helped to elucidate functional, quantitative and mechanistic aspects of the complex microorganism-host interactions that underlie human physiology and pathophysiology. The microbiome of semen is a field of increasing scientific interest, although this microbial niche is currently understudied compared with other areas of microbiome research. However, emerging evidence is beginning to indicate that the seminal microbiome has important implications for the reproductive health of men, the health of the couple and even the health of offspring, owing to transfer of microorganisms to the partner and offspring. As this field expands, further carefully designed and well-powered studies are required to unravel the true nature and role of the seminal microbiome.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.