Evidence map›Paper›PMID 31732533›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2019

STAT3 and STAT5 Signaling Thresholds Determine Distinct Regulation for Innate Receptor-Induced Inflammatory Cytokines, and

Matija Hedl, Rui Sun, Chen Huang, Clara Abraham

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Macrophage polarization in inflammatory bowel disease.Cell communication and signaling : CCS · 2023
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Proteomic analysis and identification reveal the anti-inflammatory mechanism of clofazimine on lipopolysaccharide-induced acute lung injury in mice.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2022
    Article
  13. Article
  14. Review
  15. Identification of mutations in porcineFrontiers in veterinary science · 2022
    Article
  16. Article
  17. Disease Risk-Associated Genetic Variants inJournal of immunology (Baltimore, Md. : 1950) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Matija HedlDepartment of Internal Medicine, Yale University, New Haven, CT 06510.
Rui SunDepartment of Internal Medicine, Yale University, New Haven, CT 06510.ORCID 0000-0003-4054-1365
Chen HuangDepartment of Internal Medicine, Yale University, New Haven, CT 06510.
Clara AbrahamDepartment of Internal Medicine, Yale University, New Haven, CT 06510 clara.abraham@yale.edu.
Yale University · US

Funding

Yale Liver CenterP30DK034989 · NIDDK · YALE UNIVERSITY · PI YASUKO IWAKIRI · 1986 to 2026
$31.1M
Yale University Inflammatory Bowel Disease Genetics Research CenterU01DK062422 · NIDDK · YALE UNIVERSITY · PI Ling-shiang Chuang · 2002 to 2026
$10.8M
Functional outcomes of inflammatory bowel disease associated variantsR01DK099097 · NIDDK · YALE UNIVERSITY · PI CLARA ABRAHAM · 2013 to 2026
$7.0M
Integrative Genomic Analyses of Macrophages in Crohns DiseaseR01DK106593 · NIDDK · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CHO, JUDY H. · 2016 to 2020
$3.8M
Mechanisms Regulating Innate Immune ResponsesR01AI120369 · NIAID · YALE UNIVERSITY · PI ABRAHAM, CLARA · 2016 to 2020
$2.0M
NIAID NIH HHS R01 AI120369NIDDK NIH HHS P30 DK034989NIDDK NIH HHS R01 DK099097NIDDK NIH HHS R01 DK106593NIDDK NIH HHS U01 DK062422
6 · The paper itself

Abstract

Genetic variants in the

Indexed as

Signal TransductionCytokinesDisease SusceptibilityGene ExpressionHumansInflammation MediatorsInflammatory Bowel DiseasesMacrophagesPhosphorylationSTAT3 Transcription FactorSTAT5 Transcription FactorCytokinesInflammation MediatorsSTAT3 Transcription FactorSTAT5 Transcription Factor

Identifiers

PMID31732533
PMCPMC7261200
OpenAlexW2983214899

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.