Evidence map›Paper›PMID 31732272›Full record

ArticleEcotoxicology and environmental safety2020

A toxicological study on photo-degradation products of environmental ibuprofen: Ecological and human health implications.

Nishanthi Ellepola, Talysa Ogas, Danielle N Turner, Rubi Gurung, Sabino Maldonado-Torres, Rodolfo Tello-Aburto, Praveen L Patidar, Snezna Rogelj, Menake E Piyasena, Gayan Rubasinghege

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Ecotoxicology and environmental safety, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 55 citations in OpenAlex.

  1. Article
  2. Direct photolysis of tiapride in water: deep insights into desulfonation reaction.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026
    Article
  3. Review
  4. Emerging contaminants: assessing the release of pharmaceuticals via managed aquifer recharge.Environmental science and pollution research international · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Nishanthi EllepolaDepartment of Chemistry, New Mexico Institute of Mining and Technology, Socorro, NM, 87801, USA.
Talysa OgasDepartment of Chemistry, New Mexico Institute of Mining and Technology, Socorro, NM, 87801, USA.
Danielle N TurnerDepartment of Biology, New Mexico Institute of Mining and Technology, Socorro, NM, 87801, USA.
Rubi GurungDepartment of Chemistry, New Mexico Institute of Mining and Technology, Socorro, NM, 87801, USA.
Sabino Maldonado-TorresDepartment of Chemistry, New Mexico Institute of Mining and Technology, Socorro, NM, 87801, USA.
Rodolfo Tello-AburtoDepartment of Chemistry, New Mexico Institute of Mining and Technology, Socorro, NM, 87801, USA.
Praveen L PatidarDepartment of Chemistry, New Mexico Institute of Mining and Technology, Socorro, NM, 87801, USA.
Snezna RogeljDepartment of Biology, New Mexico Institute of Mining and Technology, Socorro, NM, 87801, USA.
Menake E PiyasenaDepartment of Chemistry, New Mexico Institute of Mining and Technology, Socorro, NM, 87801, USA.
Gayan RubasinghegeDepartment of Chemistry, New Mexico Institute of Mining and Technology, Socorro, NM, 87801, USA. Electronic address: gayan.rubasinghege@nmt.edu.
New Mexico Institute of Mining and Technology · US

Funding

NM-INBRE Sequencing and Bioinformatics CoreP20GM103451 · NIGMS · NEW MEXICO STATE UNIVERSITY LAS CRUCES · PI Charlotte C. Gard · 2012 to 2026
$61.2M
NIGMS NIH HHS P20 GM103451
6 · The paper itself

Abstract

Increasing quantities of pharmaceutical waste in the environment have disrupted the balance of ecosystems, and may have subsequent effects on human health. Although a handful of previous studies have shown the impacts of pharmaceutically active compounds on the environment, the toxicological effects of their degradation products remain largely unknown. In the current study, the photo-degradation products of environmental ibuprofen were assessed for both ecotoxicological and human health effects using a series of in vitro assays. Here, six of the major degradation products are synthesized with high purity (>98%) and characterized with

Indexed as

PhotolysisAliivibrio fischeriCell SurvivalEcosystemEcotoxicologyGastrointestinal MicrobiomeHEK293 CellsHep G2 CellsHumansIbuprofenSOS Response, GeneticsWater Pollutants, ChemicalIbuprofenWater Pollutants, ChemicalCytotoxicityDegradation productsEcotoxicityGut microbiotaPharmaceuticals

Identifiers

PMID31732272
PMCPMC6893141
OpenAlexW2984914669

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.