Article in Neurobiology of aging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
1 citing paper in PubMed, 1 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
5 authors at 5 institutions in 1 country.
Lon R WhitePacific Health Research and Education Institute, Honolulu, HI, USA.
Patricia A BoyleDepartment of Behavioral Sciences, Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA.
Thomas C FosterDepartment of Neuroscience, University of Florida, Gainesville, FL, USA.
Adam H GazzaleyDepartment of Neurology, University of California, San Francisco, CA, USA.
John F DisterhoftDepartment of Physiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA. Electronic address: jdisterhoft@northwestern.edu.
Northwestern University · USPacific Health Research and Education Institute · USRush University Medical Center · USUniversity of California, San Francisco · USUniversity of Florida · US
Funding
SUPPLEMENT TO RUSH ALZHEIMERS DISEASE CENTER COREP30AG010161 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI LEURGANS, SUE E. · 1991 to 2020
$49.1M
EPIDEMIOLOGY OF NEURAL RESERVE AND NEUROBIOLOGY IN AGINGR01AG017917 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BENNETT, DAVID ALAN · 2001 to 2023
$43.3M
University of Florida Older Americans Independence Center (OAIC)P30AG028740 · NIA · UNIVERSITY OF FLORIDA · PI Peihua Qiu · 2007 to 2026
$22.8M
SLOW OUTWARD CURRENTS AND LEARNING IN AGING HIPPOCAMPUSR37AG008796 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI DISTERHOFT, JOHN F · 1999 to 2020
$9.2M
Characterizing the Behavior Profile of Healthy Cognitive AgingR01AG034374 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI PATRICIA A BOYLE · 2009 to 2026
$8.8M
Epidemiologic Study of Impaired Decision-Making in Preclinical Alzheimer's DiseasR01AG033678 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BOYLE, PATRICIA A · 2009 to 2025
$7.8M
SYNAPTIC SUBSTRATES OF AGE-DEPENDENT MEMORY DEFICITSR01AG017139 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI DISTERHOFT, JOHN F · 1999 to 2013
$4.6M
Neuropathologic substrates for motor and cognitive impairment in three existing cohort studies of Alzheimer's disease and related dementiasUF1AG057707 · NIA · STANFORD UNIVERSITY · PI MONTINE, THOMAS J, WHITE, LON RAY · 2017 to 2017
$3.9M
Apolipoprotein E2 and Brain AgingRF1AG056499 · NIA · PACIFIC HEALTH RESEARCH/ EDUCATION INST · PI GOLDGABER, DMITRY Y, WHITE, LON RAY · 2017 to 2018
$3.4M
Synaptic substrates of age-dependent memory deficitsRF1AG017139 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI DISTERHOFT, JOHN F, NICHOLSON, DANIEL A · 2016 to 2016
$2.9M
Enhancing Cognitive Control in Older Adults with Complementary InterventionsR01AG049424 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI AREAN, PATRICIA A., GAZZALEY, ADAM H · 2015 to 2019
$2.9M
Cognitive resilience to Alzheimer neuropathologic changes in the Honolulu-Asia Aging Study and the Nun StudyUF1AG053983 · NIA · PACIFIC HEALTH RESEARCH/ EDUCATION INST · PI MONTINE, THOMAS J, WHITE, LON RAY · 2016 to 2016
An accurate assessment of the impact of reserve on cognitive functioning in older individuals with brain pathology requires careful measurement of each and an assessment of the extent to which each influences the other. Studies to integrate information about molecular biology, neuropathology, behavioral aspects of cognitive decline, and cognitive resilience will be of particular importance. In addition, more work is needed to improve our understanding of the effect of systemic factors on brain health and function. It seems likely that, even in later life, the brain's plasticity may allow for a positive response to stimulation. The ultimate goal of this research is to create a validated set of variables and interventions-and to understand the biology underlying them-that are useful not only in describing an individual's cognitive state but also in identifying promising paths for treatment and prevention of cognitive decline.
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
How do we validate approaches that aim to harness reserve to improve the aging brain? · full record | OpenQuestion