Evidence map›Paper›PMID 31731946›Full record

ArticleFertility and sterility2019

Fecundability in relation to use of fertility awareness indicators in a North American preconception cohort study.

Joseph Barney Stanford, Sydney Kaye Willis, Elizabeth Elliott Hatch, Kenneth Jay Rothman, Lauren Anne Wise

Open access · greenAbstract read
In one paragraph

Article in Fertility and sterility, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 25 citations in OpenAlex.

  1. Trial
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  5. Oura Ring as a Tool for Ovulation Detection: Validation Analysis.Journal of medical Internet research · 2025
    Article
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  10. Observational
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Joseph Barney StanfordDepartment of Family and Preventive Medicine, Division of Public Health, Office of Cooperative Reproductive Health, University of Utah, Salt Lake City, Utah. Electronic address: joseph.stanford@utah.edu.
Sydney Kaye WillisDepartment of Epidemiology, Boston University School of Public Health, Boston, Massachusetts.
Elizabeth Elliott HatchDepartment of Epidemiology, Boston University School of Public Health, Boston, Massachusetts.
Kenneth Jay RothmanDepartment of Epidemiology, Boston University School of Public Health, Boston, Massachusetts; RTI International, Research Triangle Park, North Carolina.
Lauren Anne WiseDepartment of Epidemiology, Boston University School of Public Health, Boston, Massachusetts.
Boston University · USUniversity of Utah · US

Funding

An internet-based preconception cohort study in North America and DenmarkR01HD086742 · NICHD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI LAUREN A WISE · 2016 to 2026
$6.7M
Feasibility of an internet-based study of time-to-pregnancy in the United StatesR21HD072326 · NICHD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI WISE, LAUREN A · 2013 to 2014
$337k
NICHD NIH HHS R01 HD086742NICHD NIH HHS R21 HD072326
6 · The paper itself

Abstract

objectiveTo quantify the frequency of use of selected fertility awareness indicators and to assess their influence on fecundability.

designWeb-based prospective cohort study.

settingNot applicable. PATIENT(S): Female pregnancy planners, aged 21-45 years, attempting conception for ≤6 cycles at study entry. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): We ascertained time to pregnancy, in menstrual cycles, with bimonthly questionnaires. We estimated adjusted fecundability ratios (FRs) and confidence intervals (CIs) using proportional probabilities models, controlling for age, income, education, smoking, intercourse frequency, and other lifestyle and reproductive factors. RESULT(S): A total of 5,688 women were analyzed, with a mean age of 29.9 years and mean time trying of 2.1 cycles at baseline; 30% had ever been pregnant. At baseline, 75% were using one or more fertility indicators (counting days or charting menstrual cycles [71%], measuring basal body temperature [BBT, 21%], monitoring cervical fluid [39%], using urine LH tests [32%], or feeling for changes in position of the cervix [12%]). Women using any fertility indicator at baseline had higher subsequent fecundability (adjusted FR 1.25, 95% CI 1.16-1.35) than those not using any fertility indicators. For each individual indicator, adjusted FRs ranged from 1.28-1.36, where 1.00 would indicate no relation with fecundability. The adjusted FR for women using a combination of charting days, cervical fluid, and urine LH was 1.48 (95% CI 1.31-1.67) relative to women using no fertility indicators. CONCLUSION(S): In a North American preconception cohort study, use of fertility indicators indicating the fertile window was common, and was associated with greater fecundability.

Indexed as

Surveys and QuestionnairesAdultAwarenessCohort StudiesFemaleFertilityHumansNorth AmericaPreconception CarePregnancyProspective StudiesTime-to-Pregnancycohort studiesfertilityFertility awarenesspreconceptiontime to pregnancy

Identifiers

PMID31731946
PMCPMC11040510
OpenAlexW2988501484

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.