Evidence map›Paper›PMID 31731823›Full record

ArticleNanomaterials (Basel, Switzerland)2019

Development of Superparamagnetic Nanoparticles Coated with Polyacrylic Acid and Aluminum Hydroxide as an Efficient Contrast Agent for Multimodal Imaging.

Manuel Antonio González-Gómez, Sarah Belderbos, Susana Yañez-Vilar, Yolanda Piñeiro, Frederik Cleeren, Guy Bormans, Christophe M Deroose, Willy Gsell, Uwe Himmelreich, José Rivas

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 99 citations in OpenAlex.

  1. Article
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  4. [Molecules (Basel, Switzerland) · 2024
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  12. Direct Cell Radiolabeling forChemical reviews · 2022
    Review
  13. Review
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  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Coating Effect on theNanomaterials (Basel, Switzerland) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Manuel Antonio González-GómezApplied Physics Department, NANOMAG Laboratory, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain.
Sarah BelderbosBiomedical MRI, Department of Imaging and Pathology, KU Leuven, O&N I, Herestraat 49-Box 505, 3000 Leuven, Belgium.ORCID 0000-0002-4043-6007
Susana Yañez-VilarApplied Physics Department, NANOMAG Laboratory, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain.ORCID 0000-0002-0314-8567
Yolanda PiñeiroApplied Physics Department, NANOMAG Laboratory, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain.ORCID 0000-0003-4614-1629
Frederik CleerenRadiopharmaceutical Research, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, O&NII Herestraat 49-Box 821, 3000 Leuven, Belgium.
Guy BormansRadiopharmaceutical Research, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, O&NII Herestraat 49-Box 821, 3000 Leuven, Belgium.
Christophe M DerooseMolecular Small Animal Imaging Center (MoSAIC), KU Leuven, O&N I, Herestraat 49-Box 505, 3000 Leuven, Belgium.
Willy GsellBiomedical MRI, Department of Imaging and Pathology, KU Leuven, O&N I, Herestraat 49-Box 505, 3000 Leuven, Belgium.
Uwe HimmelreichBiomedical MRI, Department of Imaging and Pathology, KU Leuven, O&N I, Herestraat 49-Box 505, 3000 Leuven, Belgium.
José RivasApplied Physics Department, NANOMAG Laboratory, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain.
KU Leuven · BEUniversidade de Santiago de Compostela · ESUniversitair Ziekenhuis Leuven · BE

Funding

Flemish Agency for Innovation by Science and Technology 140061H2020 European Research Council 686009Hercules Stichting AKUL/13/29'Stichting tegen Kanker' STK 2015-145The Research Foundation - Flanders FWO; 12R3119NXunta de Galicia ED431E2018/08
6 · The paper itself

Abstract

Early diagnosis of disease and follow-up of therapy is of vital importance for appropriate patient management since it allows rapid treatment, thereby reducing mortality and improving health and quality of life with lower expenditure for health care systems. New approaches include nanomedicine-based diagnosis combined with therapy. Nanoparticles (NPs), as contrast agents for in vivo diagnosis, have the advantage of combining several imaging agents that are visible using different modalities, thereby achieving high spatial resolution, high sensitivity, high specificity, morphological, and functional information. In this work, we present the development of aluminum hydroxide nanostructures embedded with polyacrylic acid (PAA) coated iron oxide superparamagnetic nanoparticles, Fe

Indexed as

aluminum hydroxide (Al(OH)3)biomedical applicationsmagnetite (Fe3O4)MRImultimodal imagingPETsuperparamagnetic nanoparticles (SPMNPs)

Identifiers

PMID31731823
PMCPMC6915788
OpenAlexW2985186771

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.