ArticleDiagnostics (Basel, Switzerland)2019
Prefrontal Asymmetry during Cognitive Tasks and its Relationship with Suicide Ideation in Major Depressive Disorder: An fNIRS Study.
Article in Diagnostics (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Clinical Utility of Functional Near-Infrared Spectroscopy for Assessment and Prediction of Suicidality: A Systematic Review.Frontiers in psychiatry · 2021Pooled it
- Article
- Utility of Functional Near-infrared Spectroscopy (fNIRS) in Major Depressive Disorder: A Systematic Review.Indian journal of psychological medicine · 2026Review
- Modulation of subjective and objective indicators in college students with subthreshold depression by TEAS combined with five-tone music therapy.American journal of translational research · 2026Article
- Electroconvulsive therapy modulates Fronto-temporal functional connectivity in adolescents with depression and suicidal ideation.Frontiers in neuroimaging · 2026Article
- Relationship Between Darkness and Healing of Night Sky in Planetarium.International journal of environmental research and public health · 2025Article
- Prefrontal activation in bipolar and unipolar depression patients in the letter fluency tasks and category fluency tasks: a functional near-infrared spectroscopy study.Frontiers in psychiatry · 2025Article
- Reduced frontotemporal connectivity during a verbal fluency task in patients with anxiety, sleep, and major depressive disorders.Frontiers in neurology · 2025Article
- Evaluating prefrontal changes in depression using functional near-infrared spectroscopy utilizing Stroop test: A comparison with healthy controls.Indian journal of psychiatry · 2024Article
- Cortical activation for adolescent-onset minor depression and major depressive disorder: an fNIRS study.Annals of general psychiatry · 2024Article
- The Relationship between Depression Severity and Prefrontal Hemodynamic Changes in Adolescents with Major Depression Disorder: A Functional Near-infrared Spectroscopy Study.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2024Article
- Functional Near-Infrared Spectroscopy-Based Computer-Aided Diagnosis of Major Depressive Disorder Using Convolutional Neural Network with a New Channel Embedding Layer Considering Inter-Hemispheric Asymmetry in Prefrontal Hemodynamic Responses.Depression and anxiety · 2024Article
- The fNIRS evaluation of frontal and temporal lobe cortical activation in Chinese first-episode medication-naïve and recurrent depression during a verbal fluency task.Frontiers in psychiatry · 2023Article
- Intrinsic Organization of Occipital Hubs Predicts Depression: A Resting-State fNIRS Study.Brain sciences · 2022Article
- Impaired Oxygenation of the Prefrontal Cortex During Verbal Fluency Task in Young Adults With Major Depressive Disorder and Suicidality: A Functional Near-Infrared Spectroscopy Study.Frontiers in psychiatry · 2022Article
- Clinical Applications of Functional Near-Infrared Spectroscopy in Children and Adolescents with Psychiatric Disorders.Soa--ch'ongsonyon chongsin uihak = Journal of child & adolescent psychiatry · 2021Review
- A Narrative Review on Clinical Applications of fNIRS.Journal of digital imaging · 2020Review
- Frontal asymmetry as a core feature of major depression: a functional near-infrared spectroscopy study.Journal of psychiatry & neuroscience : JPNArticle
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8 authors.
Funding
Abstract
Reduced oxygenation changes in the prefrontal cortex during cognitive tasks have been reported in major depressive disorder (MDD). However, prefrontal asymmetry during cognitive tasks and its relation to suicide ideations have been less frequently examined in patients with MDD. This study investigated prefrontal asymmetry and its moderating effect on the relationship between depression severity and suicidal ideation in MDD patients during cognitive tasks. Forty-two patients with MDD and 64 healthy controls (HCs) were assessed for changes in oxygenated and deoxygenated hemoglobin (Hb) in the prefrontal cortex using functional near-infrared spectroscopy (fNIRS) during the verbal fluency task (VFT), Stroop task, and two-back task. Depression, anxiety, and suicide ideation were measured through self-report questionnaires. Relatively smaller left oxy-Hb changes during VFT, but not during the Stroop or two-back tasks, were found in MDD patients compared with HCs. Furthermore, prefrontal asymmetry during VFT moderated the effect of depression severity on suicide ideation, and was significantly and positively correlated with suicide ideation in patients with MDD. Specifically, relatively greater left oxy-Hb changes were associated with greater suicide ideation. These findings suggest fNIRS-measured prefrontal asymmetry as a potential biomarker for MDD and for the assessment of suicidal risk in patients with MDD.
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