Evidence map›Paper›PMID 31731704›Full record

ReviewAntioxidants (Basel, Switzerland)2019

Nitric Oxide-Releasing Polymeric Materials for Antimicrobial Applications: A Review.

Fan Rong, Yizhang Tang, Tengjiao Wang, Tao Feng, Jiang Song, Peng Li, Wei Huang

Open access · goldAbstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 160 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Nitric Oxide-ReleasingPharmaceutics · 2025
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Fan RongXi'an Institute of Flexible Electronics & Xi'an Institute of Biomedical Materials & Engineering, Northwestern Polytechnical University, 127 West Youyi Road, Xi'an 710072, Shaanxi, China.ORCID 0000-0002-4224-7189
Yizhang TangXi'an Institute of Flexible Electronics & Xi'an Institute of Biomedical Materials & Engineering, Northwestern Polytechnical University, 127 West Youyi Road, Xi'an 710072, Shaanxi, China.
Tengjiao WangXi'an Institute of Flexible Electronics & Xi'an Institute of Biomedical Materials & Engineering, Northwestern Polytechnical University, 127 West Youyi Road, Xi'an 710072, Shaanxi, China.ORCID 0000-0001-5100-9601
Tao FengXi'an Institute of Flexible Electronics & Xi'an Institute of Biomedical Materials & Engineering, Northwestern Polytechnical University, 127 West Youyi Road, Xi'an 710072, Shaanxi, China.
Jiang SongXi'an Institute of Flexible Electronics & Xi'an Institute of Biomedical Materials & Engineering, Northwestern Polytechnical University, 127 West Youyi Road, Xi'an 710072, Shaanxi, China.
Peng LiXi'an Institute of Flexible Electronics & Xi'an Institute of Biomedical Materials & Engineering, Northwestern Polytechnical University, 127 West Youyi Road, Xi'an 710072, Shaanxi, China.ORCID 0000-0002-5876-2177
Wei HuangXi'an Institute of Flexible Electronics & Xi'an Institute of Biomedical Materials & Engineering, Northwestern Polytechnical University, 127 West Youyi Road, Xi'an 710072, Shaanxi, China.
Northwestern Polytechnical University · CN

Funding

Fundamental Research Funds for the Central Universities Grant No. G2018KY0305Fundamental Research Funds for the Central Universities Grant No. G2018KY0307National Key Research and Development Program of China Grant No. 2018YFC1105402National Natural Science Foundation of China Grant No. 21875189Natural Science Basic Research Plan in Shaanxi Province of China Grant No. 2019JQ-157Natural Science Basic Research Plan in Shaanxi Province of China Grant No. 2019KJXX-064
6 · The paper itself

Abstract

Polymeric materials releasing nitric oxide have attracted significant attention for therapeutic use in recent years. As one of the gaseous signaling agents in eukaryotic cells, endogenously generated nitric oxide (NO) is also capable of regulating the behavior of bacteria as well as biofilm formation in many metabolic pathways. To overcome the drawbacks caused by the radical nature of NO, synthetic or natural polymers bearing NO releasing moiety have been prepared as nano-sized materials, coatings, and hydrogels. To successfully design these materials, the amount of NO released within a certain duration, the targeted pathogens and the trigger mechanisms upon external stimulation with light, temperature, and chemicals should be taken into consideration. Meanwhile, NO donors like

Indexed as

anti-bacterialanti-biofilmbiomedical devicenitric oxideNO releasing polymer

Identifiers

PMID31731704
PMCPMC6912614
OpenAlexW2987438372

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.