ArticleJournal of clinical medicine2019
High Myopia and Its Associated Factors in JPHC-NEXT Eye Study: A Cross-Sectional Observational Study.
Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 22 citations in OpenAlex.
- Photobiology in ophthalmology: from evolutionary adaptation to translational therapeutics.Japanese journal of ophthalmology · 2026Review
- Body Mass Index is Associated With Direction-Specific Increases in With-the-Rule Corneal and Refractive Astigmatism in Schoolchildren.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026Article
- Review
- Risk Factors for Adult Axial Length Elongation: A 5-Year Population-Based Cohort Study.Ophthalmology science · 2026Article
- Prevalence and related factors of high myopia among adults aged 50 years and older in Fujian Eye Study.PloS one · 2026Article
- Prevalence of high myopia and its associated factors among secondary school students at Finote-selam town, Northwest Ethiopia, 2023.Scientific reports · 2025Article
- Preliminary insights into serum metabolomics in atrophic myopic maculopathy: potential link to fatty acid metabolism dysregulation.BMC ophthalmology · 2025Article
- The correlation between intraocular pressure and choroidal microcirculation in patients with high myopia.International journal of medical sciences · 2025Observational
- Relationship between the morphology of the posterior pole of the eyeball and changes in choroidal structure and blood flow in myopia.Quantitative imaging in medicine and surgery · 2024Article
- Myopic shift in female mice after ovariectomy.Scientific reports · 2024Article
- Association between body mass index and myopia in the United States population in the National Health and Nutrition Examination Surveys 1999 to 2008: a cross-sectional study.European journal of medical research · 2023Article
- Article
- Study on Factors Associated with High Myopia CNV in Aqueous Humor and Serum.BioMed research international · 2022Article
- A Review of Intraocular Pressure (IOP) and Axial Myopia.Journal of ophthalmology · 2022Review
- Efficacy and safety of Bu Jing Yi Shi tables for high myopia: A protocol of systematic review and meta-analysis.Medicine · 2021Article
- Hyperreflective Material in Optical Coherence Tomography Images of Eyes with Myopic Choroidal Neovascularization May Affect the Visual Outcome.Journal of clinical medicine · 2020Article
- Endothelin-1 Serum Concentration is Lower in Children and Adolescents with High Myopia, a Preliminary Study.Journal of clinical medicine · 2020Article
Corrections and comments
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Authors and funding
13 authors at 3 institutions in 1 country.
Funding
Abstract
The increasing prevalence of high myopia has been noted. We investigated the epidemiological characteristics and the related factors of high myopia in a Japanese adult population. Japan Public Health Center-Based Prospective Study for the Next Generation (JPHC-NEXT) Eye Study was performed in Chikusei-city, a rural area in mid-east Japan, between 2013 and 2015. A cross-sectional observational analysis was conducted to investigate prevalence and related factors of high myopia. A total of 6101 participants aged ≥40 years without a history of ocular surgeries was included. High myopia was defined as a spherical equivalent refraction of ≤-6.00 diopters according to the American Academy of Ophthalmology. Potential high myopia-related factors included intraocular pressure (IOP), corneal structure, corneal endothelial cell density, age, height, body mass index, heart rate, blood pressure, biochemical profile, and current history of systemic and ocular disorders. The odds ratios of high myopia were estimated using the logistic regression models adjusted for the associated factors. The prevalence of high myopia was 3.8% in males and 5.9% in females with a significant difference. Age was inversely associated, IOP was positively associated, and none of other factors were associated with high myopia in both sexes. In conclusion, only age and IOP were associated with high myopia in this community-based sample.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.