Evidence map›Paper›PMID 31731565›Full record

ArticleAnimals : an open access journal from MDPI2019

Iodine Supplemented Diet Positively Affect Immune Response and Dairy Product Quality in Fresian Cow.

Marco Iannaccone, Andrea Ianni, Ramy Elgendy, Camillo Martino, Mery Giantin, Lorenzo Cerretani, Mauro Dacasto, Giuseppe Martino

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Marco IannacconeFaculty of Bioscience and Technology for Food, Agriculture, and Environment, University of Teramo, Via R. Balzarini 1, 64100 Teramo, Italy.ORCID 0000-0002-2283-6613
Andrea IanniDepartment of Medical, Oral and Biotechnological Sciences, "G. d'Annunzio" University Chieti-Pescara, Via dei Vestini 31, 66100 Chieti, Italy.ORCID 0000-0003-3102-6804
Ramy ElgendyDepartment of Immunology, Genetics and Pathology, Uppsala University, Uppsala 75185, Sweden.ORCID 0000-0002-2592-3448
Camillo MartinoIstituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise "G. Caporale" Via Campo Boario, 64100 Teramo, Italy.
Mery GiantinDepartment of Comparative Biomedicine and Food Science, University of Padua, Viale dell'Università 16, 35020 Legnaro (PD), Italy.
Lorenzo CerretaniPizzoli SPA, Via Zenzalino Nord, 40054 1 Budrio (BO), Italy.
Mauro DacastoDepartment of Comparative Biomedicine and Food Science, University of Padua, Viale dell'Università 16, 35020 Legnaro (PD), Italy.ORCID 0000-0002-3637-5643
Giuseppe MartinoFaculty of Bioscience and Technology for Food, Agriculture, and Environment, University of Teramo, Via R. Balzarini 1, 64100 Teramo, Italy.ORCID 0000-0002-7878-9318
University of Padua · ITUniversity of Teramo · ITIstituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise G. Caporale · ITUniversity of Chieti-Pescara · ITUppsala University · SE

Funding

Regione Abruzzo MISURA 1.2.4.
6 · The paper itself

Abstract

The effects of iodine supplementation on the whole-transcriptome of dairy cow using RNA sequencing has been investigated in this study. Iodine did not influence the milk composition, while an improvement was observed in the immune response as well as in the quality of dairy product. Indeed, the iodine intake specifically influenced the expression of 525 genes and the pathway analysis demonstrated that the most affected among them were related to immune response and oxidative stress. As a consequence, we indirectly showed a better response to bacterial infection because of the reduction of somatic cell counts; furthermore, an improvement of dairy product quality was observed since lipid oxidation reduced in fresh cheese. Such findings, together with the higher milk iodine content, clearly demonstrated that iodine supplementation in dairy cow could represent a beneficial practice to preserve animal health and to improve the nutraceutical properties of milk and its derived products.

Indexed as

fresh cheeseimmune responseIodineoxidative stresssomatic cell counttranscriptomics

Identifiers

PMID31731565
PMCPMC6912399
OpenAlexW2981426288

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.