Evidence map›Paper›PMID 31731540›Full record

ArticleInternational journal of molecular sciences2019

Single-Channel Properties of the ROMK-Pore-Forming Subunit of the Mitochondrial ATP-Sensitive Potassium Channel.

Michał Laskowski, Bartłomiej Augustynek, Piotr Bednarczyk, Monika Żochowska, Justyna Kalisz, Brian O'Rourke, Adam Szewczyk, Bogusz Kulawiak

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 42 citations in OpenAlex.

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  14. Mitochondrial ion channels in cardiac function.American journal of physiology. Cell physiology · 2021
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  18. Identification of the Large-Conductance CaMolecules (Basel, Switzerland) · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Michał LaskowskiLaboratory of Intracellular Ion Channels, Nencki Institute of Experimental Biology, Polish Academy of Sciences, 02-093 Warsaw, Poland.
Bartłomiej AugustynekLaboratory of Intracellular Ion Channels, Nencki Institute of Experimental Biology, Polish Academy of Sciences, 02-093 Warsaw, Poland.
Piotr BednarczykDepartment of Physics and Biophysics, Institute of Biology, Warsaw University of Life Sciences-SGGW, 02-787 Warsaw, Poland.ORCID 0000-0002-7125-0715
Monika ŻochowskaLaboratory of Intracellular Ion Channels, Nencki Institute of Experimental Biology, Polish Academy of Sciences, 02-093 Warsaw, Poland.ORCID 0000-0002-3824-4962
Justyna KaliszLaboratory of Intracellular Ion Channels, Nencki Institute of Experimental Biology, Polish Academy of Sciences, 02-093 Warsaw, Poland.ORCID 0000-0002-4188-5074
Brian O'RourkeDivision of Cardiology, The Johns Hopkins University School of Medicine, 720 Rutland Avenue, Baltimore, MD, USA.
Adam SzewczykLaboratory of Intracellular Ion Channels, Nencki Institute of Experimental Biology, Polish Academy of Sciences, 02-093 Warsaw, Poland.ORCID 0000-0001-5519-260X
Bogusz KulawiakLaboratory of Intracellular Ion Channels, Nencki Institute of Experimental Biology, Polish Academy of Sciences, 02-093 Warsaw, Poland.ORCID 0000-0002-4420-9557
Instytut Biologii Doświadczalnej im. Marcelego Nenckiego · PLJohns Hopkins University · USWarsaw University of Life Sciences · PL

Funding

Novel Mitochondrial Ion TransportersR01HL108917 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI O'ROURKE, BRIAN · 2011 to 2015
$2.3M
Molecular Determinants of Mitochondrial Instability and ArrhythmiasR01HL137259 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI AKAR, FADI GABRIEL, O'ROURKE, BRIAN · 2017 to 2020
$2.0M
NHLBI NIH HHS R01 HL137259NIH HHS R01HL108917
6 · The paper itself

Abstract

An increased flux of potassium ions into the mitochondrial matrix through the ATP-sensitive potassium channel (mitoK

Indexed as

Adenosine TriphosphateCell LineHumansMagnesiumMitochondrial MembranesMitochondrial ProteinsMyocardiumPotassium Channels, Inwardly RectifyingAdenosine TriphosphateMagnesiumMitochondrial ProteinsPotassium Channels, Inwardly RectifyingROMK2 protein, humancardiac musclemitochondriamitochondrial ATP-sensitive potassium channelmitochondrial large conductance calcium regulated potassium channelpatch-clamprenal outer medullary potassium channel

Identifiers

PMID31731540
PMCPMC6862428
OpenAlexW2982130354

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.