Evidence map›Paper›PMID 31731456›Full record

ArticleCancers2019

Tumor and Cerebrospinal Fluid microRNAs in Primary Central Nervous System Lymphomas.

Michalina Zajdel, Grzegorz Rymkiewicz, Maria Sromek, Maria Cieslikowska, Pawel Swoboda, Mariusz Kulinczak, Krzysztof Goryca, Zbigniew Bystydzienski, Katarzyna Blachnio, Beata Ostrowska and 5 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Pooled it
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  7. Updates of primary central nervous system lymphoma.Therapeutic advances in hematology · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Michalina ZajdelDepartment of Immunology, Maria Sklodowska-Curie Institute-Oncology Center, 02-781 Warsaw, Poland.
Grzegorz RymkiewiczFlow Cytometry Laboratory, Department of Pathology and Laboratory Diagnostics, Maria Sklodowska-Curie Institute-Oncology Center, 02-781 Warsaw, Poland.
Maria SromekDepartment of Immunology, Maria Sklodowska-Curie Institute-Oncology Center, 02-781 Warsaw, Poland.
Maria CieslikowskaDepartment of Immunology, Maria Sklodowska-Curie Institute-Oncology Center, 02-781 Warsaw, Poland.
Pawel SwobodaDepartment of Immunology, Maria Sklodowska-Curie Institute-Oncology Center, 02-781 Warsaw, Poland.
Mariusz KulinczakDepartment of Immunology, Maria Sklodowska-Curie Institute-Oncology Center, 02-781 Warsaw, Poland.
Krzysztof GorycaDepartment of Medical Genetics, Maria Sklodowska-Curie Institute-Oncology Center, 02-781 Warsaw, Poland.
Zbigniew BystydzienskiFlow Cytometry Laboratory, Department of Pathology and Laboratory Diagnostics, Maria Sklodowska-Curie Institute-Oncology Center, 02-781 Warsaw, Poland.
Katarzyna BlachnioFlow Cytometry Laboratory, Department of Pathology and Laboratory Diagnostics, Maria Sklodowska-Curie Institute-Oncology Center, 02-781 Warsaw, Poland.
Beata OstrowskaDepartment of Lymphoid Malignancies, Maria Sklodowska-Curie Institute-Oncology Center, 02-781 Warsaw, Poland.
Anita BorysiukFlow Cytometry Laboratory, Department of Pathology and Laboratory Diagnostics, Maria Sklodowska-Curie Institute-Oncology Center, 02-781 Warsaw, Poland.
Agnieszka Druzd-SitekDepartment of Lymphoid Malignancies, Maria Sklodowska-Curie Institute-Oncology Center, 02-781 Warsaw, Poland.
Jan WalewskiDepartment of Lymphoid Malignancies, Maria Sklodowska-Curie Institute-Oncology Center, 02-781 Warsaw, Poland.ORCID 0000-0003-4247-2674
Magdalena ChechlinskaDepartment of Immunology, Maria Sklodowska-Curie Institute-Oncology Center, 02-781 Warsaw, Poland.
Jan Konrad SiwickiDepartment of Immunology, Maria Sklodowska-Curie Institute-Oncology Center, 02-781 Warsaw, Poland.
The Maria Sklodowska-Curie National Research Institute of Oncology · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary central nervous system lymphoma (PCNSL) is a rare, highly aggressive, extranodal form of non-Hodgkin lymphoma, predominantly diagnosed as primary diffuse large B-cell lymphoma of the central nervous system (CNS DLBCL). Fast and precise diagnosis of PCNSL is critical yet challenging. microRNAs, important regulators in physiology and pathology are potential biomarkers. In 131 patients with CNS DLBCL and with non-malignant brain lesions (n-ML), miR-21, miR-19b and miR-92a, miR-155, miR-196b, miR-let-7b, miR-125b, and miR-9 were examined by RT-qPCR in brain biopsy samples (formalin-fixed paraffin-embedded tissues, FFPET; CNS DLBCL,

Indexed as

brain stereotactic biopsybrain tumorcentral nervous system (CNS) lymphomacerebrospinal fluidCNS diseasedifferential diagnosismicroRNAneurological disease

Identifiers

PMID31731456
PMCPMC6895823
OpenAlexW2981428909

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.