Evidence map›Paper›PMID 31731439›Full record

ReviewAntioxidants (Basel, Switzerland)2019

Vitamin D and Gestational Diabetes Mellitus: Is There a Link?

Gianluca Rizzo, Simone Garzon, Michele Fichera, Marco Marzio Panella, Ursula Catena, Antonio Schiattarella, Pasquale de Franciscis, George Vilos, Jan Tesarik, Péter Török and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 2 pooled it
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 2 syntheses or guidelines pooled it, 55 citations in OpenAlex.

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  15. [Correlation analysis of vitamin D level and anti-Müllerian hormone in infertile female and the role in predicting pregnancy outcome].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 3 countries.

Gianluca RizzoIndependent Researcher.ORCID 0000-0002-5540-0621
Simone GarzonDepartment of Obstetrics and Gynecology, "Filippo del Ponte" Hospital, University of Insubria, 21100 Varese, Italy.ORCID 0000-0002-5840-699X
Michele FicheraDepartment of General Surgery and Medical Surgical Specialties, University of Catania, 95124 Catania, Italy.
Marco Marzio PanellaDepartment of General Surgery and Medical Surgical Specialties, University of Catania, 95124 Catania, Italy.
Ursula CatenaDivision of Gynecologic Oncology, Fondazione Policlinico Universitario Agostino Gemelli, IRCCS, 00168 Rome, Italy.
Antonio SchiattarellaDepartment of Woman, Child and General and Specialized Surgery, University of Campania "Luigi Vanvitelli", 81100 Naples, Italy.ORCID 0000-0003-2994-1093
Pasquale de FranciscisDepartment of Woman, Child and General and Specialized Surgery, University of Campania "Luigi Vanvitelli", 81100 Naples, Italy.
George VilosDepartment of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, Western University, London, ON N6H5W9, Canada.
Jan TesarikMARGen Clinic, 18006 Granada, Spain.
Péter TörökFaculty of Medicine, Institute of Obstetrics and Gynaecology, University of Debrecen, H-4032 Debrecen, Hungary.ORCID 0000-0003-4093-3721
Giuseppe GrossoDepartment of Biomedical and Biotechnological Sciences, University of Catania, 95123 Catania, Italy.ORCID 0000-0003-3930-5285
University of Catania · ITUniversity of Campania "Luigi Vanvitelli" · ITAgostino Gemelli University Polyclinic · ITUniversity of Debrecen · HUUniversity of Insubria · ITWestern University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gestational diabetes mellitus (GDM) is a very common condition among pregnant women worldwide with important metabolic implications on the mother and the offspring. Vitamin D status has been suggested to potentially play a role in GDM risk with no documented consequences for the offspring. The purpose of this article was to review currently available evidence on the relationship between vitamin D and GDM. Current evidence shows an association between vitamin D blood levels and risk of GDM, despite heterogeneity of results across studies limit the conclusions. Moreover, data from randomized controlled trials is scarce and resulting in null findings. Among the limitations to be noted, improving the standardization of dosages, the characteristics of individuals in the sample, and the appropriate outcome measurement could provide a more effective approach in understanding the relationship between vitamin D and GDM. In conclusions, despite observational studies may suggest that adequate vitamin D levels may decrease the risk of GDM compared to deficiency status, evidence from clinical trials is inadequate to draft any definitive conclusion regarding its supplementation. Future better designed randomized clinical trials taking into account a more integrated approach could provide clearer and definitive data on the outcomes of such a multifactorial condition.

Indexed as

antenatal carefood fortificationgestational diabetes mellitusnutritionpregnancysupplementsvitamin D

Identifiers

PMID31731439
PMCPMC6912234
OpenAlexW2981385332

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.