Evidence map›Paper›PMID 31731083›Full record

ArticleInternational journal of surgery case reports2019

Paraganglion, a pitfall in diagnosis after regular cholecystectomy.

Bartholomeus J G A Corten, Wouter K G Leclercq, M Wouter Dercksen, Wilhelmus T van den Broek, Peter H van Zwam, Cees H Dejong, Gerrit D Slooter

Open access · goldAbstract read
In one paragraph

Article in International journal of surgery case reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 81% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Bartholomeus J G A CortenDepartment of Surgery, Máxima Medical Center, Veldhoven, the Netherlands. Electronic address: bartcorten@gmail.com.
Wouter K G LeclercqDepartment of Surgery, Máxima Medical Center, Veldhoven, the Netherlands.
M Wouter DercksenDepartment of Internal Medicine, Máxima Medical Center, Veldhoven, the Netherlands.
Wilhelmus T van den BroekDepartment of Surgery, St, Anna Hospital, Geldrop, the Netherlands.
Peter H van ZwamDepartment of Pathology, PAMM Laboratory for Pathology and Medical Microbiology, Eindhoven, the Netherlands.
Cees H DejongDepartment of Surgery, Maastricht University Medical Centre, Maastricht, the Netherlands.
Gerrit D SlooterDepartment of Surgery, Máxima Medical Center, Veldhoven, the Netherlands.
Máxima Medisch Centrum · NLMaastricht University Medical Centre · NLPAMM · NLRadboud University Nijmegen · NLSt. Anna Ziekenhuis · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionNeuroendocrine neoplasm of the gallbladder is an extremely uncommon diagnosis. We present a case of a benign gallbladder paraganglion that was initially incorrectly diagnosed as a neuroendocrine tumour (NET). PRESENTATION OF CASE: A 27-year-old female with symptomatic gallstone disease underwent an uncomplicated laparoscopic cholecystectomy. Routine histopathologic examination suggested the presence of a small adventitial NET. However, histopathological revision was performed by our pathologist because of regional gallbladder carcinoma (GBC) treatment evaluation. The revision demonstrated the presence of a normal paraganglion, a preexistent structure that is only rarely encountered during routine histopathologic examination of the gallbladder. DISCUSSION: Neuroendocrine neoplasms of the gallbladder are extremely rare. Treatment varies from a simple cholecystectomy to extensive surgical resections. Chemotherapy is usually reserved for metastatic disease. In contrast, a gallbladder paraganglion is a benign entity not requiring additional treatment.

conclusionA neuroendocrine neoplasm of the gallbladder may closely resemble a benign paraganglion. If a NET is suspected, the clinician should be aware of the histopathologic mimicry of a paraganglion prior to initiating additional treatments.

Indexed as

Gallbladder cancerNeuroendocrine neoplasmNeuroendocrine tumourParaganglion

Identifiers

PMID31731083
PMCPMC6920188
OpenAlexW2982681042

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.