ArticleNeurotoxicology2020
Blood manganese levels during pregnancy and postpartum depression: A cohort study among women in Mexico.
Article in Neurotoxicology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Sexual dimorphism in the programming effects of prenatal manganese multi-media biomarker on temporal cognition in school-aged children.Scientific reports · 2026Article
- Environmental Chemicals and Maternal Depression During and After Pregnancy: a Scoping Review.Current environmental health reports · 2026Article
- Air pollution and postpartum depression: the interplay with prenatal stress.Research square · 2026Article
- A prospective study of a whole blood metal mixture and depressive symptoms among Black women from Detroit, Michigan.Neurotoxicology · 2025Article
- Sleep duration mediates the association between heavy metals and the prevalence of depression: an integrated approach from the NHANES (2005-2020).Frontiers in psychiatry · 2024Article
- Prenatal manganese biomarkers and operant test battery performance in Mexican children: Effect modification by child sex.Environmental research · 2023Article
- Trace Elements Levels in Major Depressive Disorder-Evaluation of Potential Threats and Possible Therapeutic Approaches.International journal of molecular sciences · 2023Review
- Early pregnancy essential and non-essential metal mixtures and maternal antepartum and postpartum depressive symptoms.Neurotoxicology · 2023Article
- Prenatal trace elements mixture is associated with learning deficits on a behavioral acquisition task among young children.New directions for child and adolescent development · 2022Article
- Exposure to environmental chemicals and perinatal psychopathology.Biochemical pharmacology · 2022Review
- Review
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
backgroundOccupational studies have shown an association between elevated Mn exposure and depressive symptoms. Blood Mn (BMn) naturally rises during pregnancy due to mobilization from tissues, suggesting it could contribute to pregnancy and postpartum depressive symptoms.
objectivesTo assess the association between BMn levels during pregnancy and postpartum depression (PPD), creating opportunities for possible future interventions.
methodsWe studied 561 women from the reproductive longitudinal Programming Research in Obesity, Growth, Environment, and Social Stressors (PROGRESS) cohort in Mexico City. BMn was measured at the 2
resultsThe mean ± standard deviation (SD) EPDS score at 12-months postpartum was 6.51 ± 5.65, and 17.11% of women met the criteria for possible PPD (score ≥ 13). In adjusted models, BMn during the 3 DISCUSSION: Our results demonstrate that elevated BMn levels during pregnancy predict PPD symptoms and could be a potential pathway for intervention and prevention of PPD.
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