Evidence map›Paper›PMID 31730881›Full record

ArticleMagnetic resonance imaging2020

Analysis of dynamic texture and spatial spectral descriptors of dynamic contrast-enhanced brain magnetic resonance images for studying small vessel disease.

Jose Bernal, Maria Del C Valdés-Hernández, Javier Escudero, Linda Viksne, Anna K Heye, Paul A Armitage, Stephen Makin, Rhian M Touyz, Joanna M Wardlaw

Abstract read
In one paragraph

Article in Magnetic resonance imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. A bibliometric analysis of cerebral small vessel disease.Frontiers in aging neuroscience · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jose BernalCentre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK. Electronic address: jose.bernal@ed.ac.uk.
Maria Del C Valdés-HernándezCentre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK. Electronic address: m.valdes-hernan@ed.ac.uk.
Javier EscuderoSchool of Engineering, University of Edinburgh, Edinburgh, UK.
Linda ViksneCentre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.
Anna K HeyeCentre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.
Paul A ArmitageAcademic Unit of Radiology, University of Sheffield, Sheffield, UK.
Stephen MakinInstitute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.
Rhian M TouyzInstitute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.
Joanna M WardlawCentre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.

Funding

Chief Scientist Office ETM/326Medical Research Council MR/J006971/1Wellcome Trust
6 · The paper itself

Abstract

Cerebral small vessel disease (SVD) comprises various pathological processes affecting small brain vessels and damaging white and grey matter. In this paper, we propose a framework comprising region of interest sampling, dynamic spectral and texture description, functional principal component analysis, and statistical analysis to study exogenous contrast agent distribution over time in various brain regions in patients with recent mild stroke and SVD features.We compared our results against current semi-quantitative surrogates of dysfunction such as signal enhancement area and slope. Biological sex, stroke lesion type and overall burden of white matter hyperintensities (WMH) were significant predictors of intensity, spectral, and texture features extracted from the ventricular region (p-value < 0.05), explaining between a fifth and a fourth of the data variance (0.20 ≤Adj.R

Indexed as

Contrast MediaAdultAgedAged, 80 and overCerebral ArteriesCerebral Small Vessel DiseasesCerebral VeinsFemaleHumansImage EnhancementMagnetic Resonance ImagingMagnetic Resonance SpectroscopyMaleMicrovesselsMiddle AgedContrast MediaCerebral small vessel diseaseDynamic brain magnetic resonance imageDynamic descriptorsPrincipal component analysis

Identifiers

PMID31730881
PMCPMC7049910

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.