Trial reportChest2020
Validation of the COPD Assessment Test (CAT) as an Outcome Measure in Bronchiectasis.
Trial report in Chest, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Psychometrics of health-related quality of life questionnaires in bronchiectasis: a systematic review and meta-analysis.The European respiratory journal · 2021Pooled it
- Clinical Efficacy of Smartphone App-Based Pulmonary Rehabilitation in Chronic Respiratory Diseases: Randomized Controlled and Feasibility Trials.Journal of medical Internet research · 2025Trial
- Forest bathing improves inflammatory markers, SpO2, and subjective symptoms related to chronic obstructive pulmonary disease (COPD) in male subjects at risk of developing COPD.Journal of occupational health · 2025Trial
- Improvement of respiratory symptoms and health-related quality of life with peramivir in influenza patients with chronic respiratory disease: Additional outcomes of a randomized, open-label study.Influenza and other respiratory viruses · 2021Trial
- The importance of symptoms in bronchiectasis.European respiratory review : an official journal of the European Respiratory Society · 2026Review
- The Chronic Airways Assessment Test (CAAT™): Evolution From the COPD Assessment Test (CAT™).Chronic obstructive pulmonary diseases (Miami, Fla.) · 2025Article
- Leveraging Subjective Parameters and Biomarkers in Machine Learning Models: The Feasibility ofDiagnostics (Basel, Switzerland) · 2025Article
- Cough in pulmonary rehabilitation: a retrospective analysis of responders and nonresponders.ERJ open research · 2025Article
- Relationship Between Social Support, Symptom Burden, Dyspnea, Perceived Stress, Perceived Stigma, Coping Styles, and Psychological Distress in Patients with Stable COPD: A Structural Equation Model.International journal of chronic obstructive pulmonary disease · 2025Observational
- Effect of dual bronchodilators plus preoperative rehabilitation in operable LC & chronic obstructive pulmonary disease.Future oncology (London, England) · 2024Article
- Article
- COPD Assessment Test and risk of readmission in patients with bronchiectasis: a prospective cohort study.ERJ open research · 2024Article
- Sputum pathogen spectrum and clinical outcomes of upper respiratory tract infection in bronchiectasis exacerbation: a prospective cohort study.Emerging microbes & infections · 2023Article
- Developing a home-based pulmonary rehabilitation programme for patients with chronic respiratory diseases in Malaysia: A mixed-method feasibility study.Journal of global health · 2023Article
- Feasibility of home initiation of an airway clearance device (SIMEOX) by telecare in people with non-cystic fibrosis bronchiectasis: a pilot study.BMJ open respiratory research · 2023Article
- The BED-Pro Tool: facilitating the detection of bronchiectasis exacerbations.ERJ open research · 2023Article
- Psychological distress and its associated factors among patients with chronic obstructive pulmonary disease in Hunan, China: a cross-sectional study.Scientific reports · 2023Article
- Relationship between serum Th1/Th2 imbalance and depression in elderly patients with COPD and its clinical implications.Technology and health care : official journal of the European Society for Engineering and Medicine · 2023Article
- Psychometric Validation of the German Translation of the Quality of Life Questionnaire-Bronchiectasis (QOL-B)-Data from the German Bronchiectasis Registry PROGNOSIS.Journal of clinical medicine · 2022Article
- Metabolomic profiling of anaerobic and aerobic energy metabolic pathways in chronic obstructive pulmonary disease.Experimental biology and medicine (Maywood, N.J.) · 2021Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundObjective assessment of symptoms in bronchiectasis is important for research and in clinical practice. The COPD Assessment Test (CAT) is a short, simple assessment tool widely used in COPD. The items included in the CAT are not specific to COPD and also reflect the dominant symptoms of bronchiectasis. We therefore performed a study to validate the CAT as an outcome measure in bronchiectasis.
methodsThe CAT was administered to two cohorts of bronchiectasis patients along with other quality of life questionnaires. Patients underwent comprehensive clinical assessment. One cohort had repeated questionnaires collected before-and-after treatment of acute exacerbations. We analyzed convergent validity, repeatability, and responsiveness of the score and calculated the minimum clinically important difference (MCID) using a combination of distribution and anchor-based methods.
resultsIn both cohorts there were positive correlations between the CAT and the St. George's Respiratory Questionnaire (r = 0.90, P < .0001 and r = 0.87, P < .0001). There was an inverse relationship between CAT and Quality of Life - Bronchiectasis Respiratory Symptoms Scale (r = -0.75, P < .0001) and Leicester Cough Questionnaire score (r = -0.77, P < .0001). Patients with more severe disease, based on the bronchiectasis severity index, had significantly higher CAT scores. CAT also correlated with FEV
conclusionsCAT is a valid, responsive symptom assessment tool in bronchiectasis. The MCID is estimated as 4 points.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.