Evidence map›Paper›PMID 31730736›Full record

ArticleDepression and anxiety2020

The short-term dynamics of posttraumatic stress disorder symptoms during the acute posttrauma period.

Matthew Price, Alison C Legrand, Zoe M F Brier, Jennifer Gratton, Christian Skalka

Abstract read
In one paragraph

Article in Depression and anxiety, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Matthew PriceDepartment of Psychological Science, Center for Research on Emotion, Stress, and Technology, University of Vermont, Burlington, Vermont.ORCID 0000-0001-5637-9230
Alison C LegrandDepartment of Psychological Science, Center for Research on Emotion, Stress, and Technology, University of Vermont, Burlington, Vermont.
Zoe M F BrierDepartment of Psychological Science, Center for Research on Emotion, Stress, and Technology, University of Vermont, Burlington, Vermont.
Jennifer GrattonDivision of Acute Care Surgery, Department of Surgery, Larner College of Medicine, University of Vermont, Burlington, Vermont.
Christian SkalkaDepartment of Computer Science, University of Vermont, Burlington, Vermont.

Funding

Evaluation of neurobiological models of adolescent maltreatment through machine learningK08MH107661 · NIMH · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI PRICE, MATTHEW · 2016 to 2019
$706k
NIMH NIH HHS 1 K08 MH107661‐01A1NIMH NIH HHS K08 MH107661
6 · The paper itself

Abstract

backgroundThe manner in which posttraumatic stress disorder (PTSD) develops remains largely unknown. PTSD is comprised of 20 symptoms across 4 clusters. These clusters were hypothesized to reflect a failure of recovery model in which intrusive symptoms appear first. Intrusive symptoms led to avoidance of trauma-related stimuli, which resulted in sustained arousal. The sustained arousal ultimately led to dysphoria.

methodsThis hypothesized symptom progression was evaluated during the acute posttrauma period (the first 30 days postevent). Participants (N = 80) reported their PTSD symptoms for 30 days via mobile devices. Using a short-term dynamic modeling framework, a temporal and contemporaneous model of PTSD symptoms was obtained.

resultsIn the temporal network, a fear-conditioning component was identified that supported the hypothesized set of relations among symptom clusters. The contemporaneous network was classified by two subnetworks. The first corresponded to a fear-conditioning model that included symptoms of intrusions and avoidance. The second included symptoms of dysphoria and arousal.

conclusionsThese findings suggest that, after a trauma, there may be a fear-conditioning process that involves intrusions, avoidance, and arousal symptoms. Dysphoric symptoms were also present but developed as a partially distinct component.

Indexed as

Major Depressive DisorderStress Disorders, Post-TraumaticArousalHumansPTSDstresstrauma

Identifiers

PMID31730736
PMCPMC8340953

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.