Evidence map›Paper›PMID 31730601›Full record

Trial reportClinical journal of oncology nursing2019

Clinical Trials: Understanding Patient Perspectives and Beliefs About Treatment.

Betty Ferrell, Anna Cathy Williams, Tami Borneman, Vincent Chung, Thomas J Smith

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Clinical journal of oncology nursing, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Use of supportive care services and advance care planning among early phase oncology clinical trial participants.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  4. Article
  5. Article
  6. Patient Perspectives on Evolving Diverticulitis Treatment: An Assessment of Patient Willingness to Enroll in a Randomized Controlled Trial.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2024
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Betty FerrellCity of Hope National Medical Center.
Anna Cathy WilliamsCity of Hope National Medical Center.
Tami BornemanCity of Hope National Medical Center.
Vincent ChungCity of Hope National Medical Center.
Thomas J SmithJohns Hopkins Sidney Kimmel Comprehensive Cancer Center.

Funding

Transgenic Mouse FacilityP30CA033572 · NCI · CITY OF HOPE/BECKMAN RESEARCH INSTITUTE · PI STANLEY R. HAMILTON · 1985 to 2026
$86.3M
Integration of Palliative Care for Cancer Patients on Phase I TrialsR01CA177562 · NCI · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI FERRELL, BETTY R · 2014 to 2018
$6.8M
NCI NIH HHS P30 CA033572NCI NIH HHS R01 CA177562
6 · The paper itself

Abstract

backgroundUnderstanding the experiences of patients with solid tumors who are in phase 1 clinical trials can help nurses to provide optimal care.

objectivesThe purpose of this article is to describe patient perspectives of participating in a phase 1 trial and understanding their disease status and treatment options. In addition, the authors describe the impact of the disease and clinical trial participation on quality of life.

methods30 patients were interviewed and audio recorded; the interviews were transcribed and content analysis methods were used to identify common themes.

findingsPatients reported participating in the phase 1 clinical trial because their doctors informed and encouraged them, they had no other treatment options if they wanted to live longer, or they wanted to help future patients with cancer. Most believed that participation would improve or stabilize their illness and quality of life. They believed that, when the clinical trial ended, there would be new treatments. Participants reported that healthcare providers and family members provided support, and that compassion, cultural awareness, spiritual support, and the need for individual attention were important.

Indexed as

Clinical Trials, Phase I as TopicAgedAged, 80 and overFemaleHumansMaleMiddle AgedNeoplasmsPatientsQuality of Lifenew treatment optionspatient perspectivephase 1 clinical trialquality of life

Identifiers

PMID31730601
PMCPMC9059412

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.