Evidence map›Paper›PMID 31730494›Full record

ReviewJournal of neuroengineering and rehabilitation2019

Beyond the target area: an integrative view of tDCS-induced motor cortex modulation in patients and athletes.

Edgard Morya, Kátia Monte-Silva, Marom Bikson, Zeinab Esmaeilpour, Claudinei Eduardo Biazoli, Andre Fonseca, Tommaso Bocci, Faranak Farzan, Raaj Chatterjee, Jeffrey M Hausdorff and 12 more

2 registry-linked trialsOpen access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of neuroengineering and rehabilitation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 69 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed, 4 pooled it
8.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05781412 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Modulation of the Activity in the Cerebellum With Transcranial Direct Current Stimulation in Autistic Participants

TypeinterventionalSponsorBeatriz CatoiraRan2022 to 2024Enrolled100ConditionsAutism Spectrum DisorderArmstDCS
NCT05886647 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Non-invasive Neurostimulation and Rehabilitation in the Treatment of Patients With Respiratory Disorders: Randomized Controlled Clinical Trial

TypeinterventionalSponsorSuellen AndradeRan2023 to 2024Enrolled30ConditionsLung DiseasesArmsActive non-invasive stimulation and inspiratory muscle training, Sham compatorator and inspiratory muscle training
3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 4 syntheses or guidelines pooled it, 170 citations in OpenAlex.

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  5. Effects of Transcranial Direct Current Stimulation and Individualized Physical Therapy on Pain and Function in Individuals With Chronic Knee Pain: A Pilot Study.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2026
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9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 14 institutions in 6 countries.

Edgard MoryaEdmond and Lily Safra International Institute of Neuroscience, Santos Dumont Institute, Macaíba, Rio Grande do Norte, Brazil.
Kátia Monte-SilvaUniversidade Federal de Pernambuco, Recife, Pernambuco, Brazil.
Marom BiksonDepartment of Biomedical Engineering, The City College of New York of CUNY, New York, New York, USA.
Zeinab EsmaeilpourDepartment of Biomedical Engineering, The City College of New York of CUNY, New York, New York, USA.
Claudinei Eduardo BiazoliCenter of Mathematics, Computing and Cognition, Universidade Federal do ABC, São Bernardo do Campo, São Paulo, Brazil.
Andre FonsecaBrazilian Institute of Neuroscience and Neurotechnology (BRAINN/CEPID-FAPESP), University of Campinas, Campinas, São Paulo, Brazil.
Tommaso BocciAldo Ravelli Center for Neurotechnology and Experimental Brain Therapeutics, Department of Health Sciences, International Medical School, University of Milan, Milan, Italy.
Faranak FarzanSchool of Mechatronic Systems Engineering, Simon Fraser University, Surrey, British Columbia, Canada.
Raaj ChatterjeeSchool of Mechatronic Systems Engineering, Simon Fraser University, Surrey, British Columbia, Canada.
Jeffrey M HausdorffDepartment of Physical Therapy, Sackler Faculty of Medicine and Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel; Rush Alzheimer's Disease Center and Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, Il, USA.
Daniel Gomes da Silva MachadoGraduate Program in Physical Education. State University of Londrina, Londrina, Paraná, Brazil.
André Russowsky BrunoniLaboratory of Neuroscience (LIM-27), Universidade de São Paulo, São Paulo, São Paulo, Brazil.
Eva MezgerDepartment of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Munich, Germany.
Luciane Aparecida MoscaleskiBrazilian Institute of Neuroscience and Neurotechnology (BRAINN/CEPID-FAPESP), University of Campinas, Campinas, São Paulo, Brazil.
Rodrigo PegadoGraduate Program in Rehabilitation Science, Universidade Federal do Rio Grande do Norte, Santa Cruz, Rio Grande do Norte, Brazil.
João Ricardo SatoCenter of Mathematics, Computing and Cognition, Universidade Federal do ABC, São Bernardo do Campo, São Paulo, Brazil.
Marcelo Salvador CaetanoCenter of Mathematics, Computing and Cognition, Universidade Federal do ABC, São Bernardo do Campo, São Paulo, Brazil.
Kátia Nunes SáNúcleo de Assistência e Pesquisa em Neuromodulação (NAPeN), Santo André, Brazil.
Clarice TanakaNúcleo de Assistência e Pesquisa em Neuromodulação (NAPeN), Santo André, Brazil.
Li Min LiBrazilian Institute of Neuroscience and Neurotechnology (BRAINN/CEPID-FAPESP), University of Campinas, Campinas, São Paulo, Brazil.
Abrahão Fontes BaptistaBrazilian Institute of Neuroscience and Neurotechnology (BRAINN/CEPID-FAPESP), University of Campinas, Campinas, São Paulo, Brazil.
Alexandre Hideki OkanoBrazilian Institute of Neuroscience and Neurotechnology (BRAINN/CEPID-FAPESP), University of Campinas, Campinas, São Paulo, Brazil. alexandre.okano@ufabc.edu.br.ORCID 0000-0002-8995-1392
Universidade Estadual de Campinas (UNICAMP) · BRCity College of New York · USEscola Bahiana de Medicina e Saúde Pública · BRSimon Fraser University · CAUniversidade Estadual de Londrina · BRUniversidade Federal do ABC · BRInstituto Nacional de Ciência e Tecnologia de Doenças Tropicais · BRLMU Klinikum · DERush University Medical Center · USUniversidade de São Paulo · BRUniversidade Federal de Pernambuco · BRUniversidade Federal do Rio Grande do Norte · BRUniversidade São Francisco · BRUniversity of Milan · IT

Funding

Training and Career Development CoreU54CA132378 · NCI · CITY COLLEGE OF NEW YORK · PI Tim Alan Ahles, ADRIANA ESPINOSA · 2008 to 2026
$28.9M
Training and Career Development and Education CoreU54CA137788 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI ADRIANA ESPINOSA, FRANCESCA M GANY · 2008 to 2026
$28.1M
A tool-box to control and enhance tDCS spatial precisionR01MH111896 · NIMH · CITY COLLEGE OF NEW YORK · PI BIKSON, MAROM · 2016 to 2019
$2.2M
The coupled vascular hypothesis for transcranial direct current stimulation (tDCS)R01NS101362 · NINDS · CITY COLLEGE OF NEW YORK · PI BIKSON, MAROM · 2017 to 2021
$1.7M
Mechanisms of Deep Brain Stimulation: Joule Heating and ElectroporationR03NS054783 · NINDS · CITY COLLEGE OF NEW YORK · PI BIKSON, MAROM · 2007 to 2008
$153k
NCI NIH HHS U54 CA132378NCI NIH HHS U54 CA137788NIMH NIH HHS R01 MH111896NINDS NIH HHS R01 NS101362NINDS NIH HHS R03 NS054783
6 · The paper itself

Abstract

Transcranial Direct Current Stimulation (tDCS) is a non-invasive technique used to modulate neural tissue. Neuromodulation apparently improves cognitive functions in several neurologic diseases treatment and sports performance. In this study, we present a comprehensive, integrative review of tDCS for motor rehabilitation and motor learning in healthy individuals, athletes and multiple neurologic and neuropsychiatric conditions. We also report on neuromodulation mechanisms, main applications, current knowledge including areas such as language, embodied cognition, functional and social aspects, and future directions. We present the use and perspectives of new developments in tDCS technology, namely high-definition tDCS (HD-tDCS) which promises to overcome one of the main tDCS limitation (i.e., low focality) and its application for neurological disease, pain relief, and motor learning/rehabilitation. Finally, we provided information regarding the Transcutaneous Spinal Direct Current Stimulation (tsDCS) in clinical applications, Cerebellar tDCS (ctDCS) and its influence on motor learning, and TMS combined with electroencephalography (EEG) as a tool to evaluate tDCS effects on brain function.

Indexed as

AthletesHealthy VolunteersHumansLearningMotor CortexNervous System DiseasesTranscranial Direct Current StimulationConnectivityctDCSHD-tDCSMotor learningMotor performanceMotor rehabilitationNeuromodulationNon-invasive brain stimulationSportTMS-evoked potentialtsDCS

Identifiers

PMID31730494
PMCPMC6858746
OpenAlexW2989135706

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.