ReviewAnnual review of physiology2020
Aging and Lung Disease.
Review in Annual review of physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 286 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
286 citing papers in PubMed, 6 syntheses or guidelines pooled it, 448 citations in OpenAlex.
- Preoperative risk factors for postoperative pneumonia in patients with esophageal cancer: A systematic review and meta-analysis.Surgery today · 2026Pooled it
- The evolving role of regulatory T cells in pulmonary diseases: immunomodulatory mechanisms and translational directions revealed by bibliometric analysis.Frontiers in medicine · 2026Pooled it
- Incidence and Risk Factors for Progression from Pre-COPD to COPD: A Systematic Review and Meta‑analysis.International journal of chronic obstructive pulmonary disease · 2026Pooled it
- Advances in Molecular Research of Tracheobronchial Tree Aging: A Systematic Review.International journal of molecular sciences · 2025Pooled it
- Associated factors in the development of rapidly progressive interstitial lung disease in patients with idiopathic inflammatory myopathies: a systematic review and meta-analysis.Frontiers in immunology · 2025Pooled it
- Effects of smoking cessation on individuals with COPD: a systematic review and meta-analysis.Frontiers in public health · 2024Pooled it
- Remimazolam Reduces the Cough Reflexes in Elderly Patients Undergoing Fiberoptic Bronchoscopy Under Remifentanil/Cipepofol-Based Anaesthesia: A Randomized Clinical Trial.Drug design, development and therapy · 2026Trial
- Cumulative Effects of Concurrent Inspiratory Muscle Training and Postural Correction Bands on Older Individuals Community Dwellers: A Randomized Study.Yonsei medical journal · 2024Trial
- Mapping Scandinavian Hospital-at-Home Organisations and Interventions for Patients With Acute Somatic Illness-A Scoping Review.Scandinavian journal of caring sciences · 2026Article
- mExperimental and therapeutic medicine · 2026Review
- Application value of the impulse oscillometry system in the airway evaluation of patients with chronic obstructive pulmonary disease in different age groups.Internal medicine journal · 2026Article
- Integration of clinical variables and CT radiomics features in a nomogram for predicting interstitial lung disease in Sjögren's syndrome.Journal of thoracic disease · 2026Article
- Predictors of delayed extubation post-coronary artery bypass graft and its relationship with length of stay and in-hospital mortality in Jordan.Acute and critical care · 2026Article
- Cellular hallmarks and aging clock of the human lung parenchyma.Nature communications · 2026Article
- Optimized Open-Source Setting for Subjecting Rodents to Chronic Normobaric Hypoxia in Facilities with Minimal Nitrogen Supply.Life (Basel, Switzerland) · 2026Article
- Association between food insecurity and healthy ageing: two population-based studies.Nutrition journal · 2026Article
- Plasma proteomic profiling uncovers the age-related molecular changes in chronic obstructive pulmonary disease.BMC pulmonary medicine · 2026Article
- Plasma albumin and other indicators as risk factors for delayed neurocognitive recovery in elderly patients undergoing orthopedic surgery.BMC surgery · 2026Article
- Sex-specific trends in incidence and mortality of interstitial lung disease and pulmonary sarcoidosis in China compared with global estimates, 1990-2023: an analysis of GBD 2023.Journal of thoracic disease · 2026Article
- Treatment of pulmonary fibrosis: From disease mechanisms to future novel therapies (Review).International journal of molecular medicine · 2026Review
226 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
People worldwide are living longer, and it is estimated that by 2050, the proportion of the world's population over 60 years of age will nearly double. Natural lung aging is associated with molecular and physiological changes that cause alterations in lung function, diminished pulmonary remodeling and regenerative capacity, and increased susceptibility to acute and chronic lung diseases. As the aging population rapidly grows, it is essential to examine how alterations in cellular function and cell-to-cell interactions of pulmonary resident cells and systemic immune cells contribute to a higher risk of increased susceptibility to infection and development of chronic diseases, such as chronic obstructive pulmonary disease and interstitial pulmonary fibrosis. This review provides an overview of physiological, structural, and cellular changes in the aging lung and immune system that facilitate the development and progression of disease.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.