Evidence map›Paper›PMID 31730015›Full record

ArticleCancer imaging : the official publication of the International Cancer Imaging Society2019

Diffusion-weighted imaging for identifying patients at high risk of tumor recurrence following liver transplantation.

Yi-Hsuan Chuang, Hsin-You Ou, Chun-Yen Yu, Chao-Long Chen, Ching-Chun Weng, Leo Leung-Chit Tsang, Hsien-Wen Hsu, Wei-Xiong Lim, Tung-Liang Huang, Yu-Fan Cheng

Abstract readEvaluation Study
In one paragraph

Article in Cancer imaging : the official publication of the International Cancer Imaging Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Diffusion-based virtual MR elastography for predicting recurrence of solitary hepatocellular carcinoma after hepatectomy.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Patient Selection for Downstaging of Hepatocellular Carcinoma Prior to Liver Transplantation-Adjusting the Odds?Transplant international : official journal of the European Society for Organ Transplantation · 2022
    Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yi-Hsuan ChuangLiver Transplantation Program, Department of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, 123 Dapi Rd, Niaosong Dist, Kaohsiung, Taiwan, Republic of China.
Hsin-You OuLiver Transplantation Program, Department of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, 123 Dapi Rd, Niaosong Dist, Kaohsiung, Taiwan, Republic of China.
Chun-Yen YuLiver Transplantation Program, Department of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, 123 Dapi Rd, Niaosong Dist, Kaohsiung, Taiwan, Republic of China.
Chao-Long ChenLiver Transplantation Program, Department of Surgery, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Ching-Chun WengLiver Transplantation Program, Department of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, 123 Dapi Rd, Niaosong Dist, Kaohsiung, Taiwan, Republic of China.
Leo Leung-Chit TsangLiver Transplantation Program, Department of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, 123 Dapi Rd, Niaosong Dist, Kaohsiung, Taiwan, Republic of China.
Hsien-Wen HsuLiver Transplantation Program, Department of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, 123 Dapi Rd, Niaosong Dist, Kaohsiung, Taiwan, Republic of China.
Wei-Xiong LimLiver Transplantation Program, Department of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, 123 Dapi Rd, Niaosong Dist, Kaohsiung, Taiwan, Republic of China.
Tung-Liang HuangLiver Transplantation Program, Department of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, 123 Dapi Rd, Niaosong Dist, Kaohsiung, Taiwan, Republic of China.
Yu-Fan ChengLiver Transplantation Program, Department of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, 123 Dapi Rd, Niaosong Dist, Kaohsiung, Taiwan, Republic of China. prof.chengyufan@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTumor recurrence is the major risk factor affecting post-transplant survival. In this retrospective study, we evaluate the prognostic values of magnetic resonance (MR) diffusion-weighted imaging (DWI) in liver transplantation for hepatocellular carcinoma (HCC).

methodsFrom April 2014 to September 2016, 106 HCC patients receiving living donor liver transplantation (LDLT) were enrolled. Nine patients were excluded due to postoperative death within 3 months and incomplete imaging data. The association between tumor recurrence, explant pathologic findings, and DWI parameters was analyzed (tumor-to-liver diffusion weighted imaging ratio, DWI

resultsSixteen of 97 patients (16%) developed tumor recurrence during the follow-up period (median of 40.9 months; range 5.2-56.5). In those with no viable tumor (n = 65) on pretransplant imaging, recurrence occurred only in 5 (7.6%) patients. Low minimum ADC values (p = 0.001), unfavorable tumor histopathology (p <  0.001) and the presence of microvascular invasion (p <  0.001) were risk factors for tumor recurrence, while ADC

conclusionsQuantitative measurement of ADC

Indexed as

AdultAgedCarcinoma, HepatocellularDiffusion Magnetic Resonance ImagingFemaleHumansLiver NeoplasmsLiver TransplantationLiving DonorsMaleMiddle AgedNeoplasm Recurrence, LocalPostoperative ComplicationsPrognosisSurvival RateADC valueDiffusion weighted imagingTumor recurrence

Identifiers

PMID31730015
PMCPMC6858682

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.