ArticleLipids in health and disease2019
Association between height and hypercholesterolemia in adults: a nationwide population-based study in Korea.
Article in Lipids in health and disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 23 citations in OpenAlex.
- Insights from the largest diverse ancestry sex-specific disease map for genetically predicted height.NPJ genomic medicine · 2025Article
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- Mediation of the association between sleep disorders and cardiovascular disease by depressive symptoms: An analysis of the National health and Nutrition Examination Survey (NHANES) 2017-2020.Preventive medicine reports · 2023Article
- A machine learning approach to personalized predictors of dyslipidemia: a cohort study.Frontiers in public health · 2023Article
- Article
- Body height among adult male and female Swiss Health Survey participants in 2017: Trends by birth years and associations with self-reported health status and life satisfaction.Preventive medicine reports · 2022Article
- Your height affects your health: genetic determinants and health-related outcomes in Taiwan.BMC medicine · 2022Article
- An inverse association of weight and the occurrence of asymptomatic gallbladder stone disease in hypercholesterolemia patients: a case-control study.Lipids in health and disease · 2020Article
- Short adult height increases the risk of end-stage renal disease in type 2 diabetes.Endocrine connections · 2020Article
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrevious studies reported that stature is inversely related to the risk of cardiovascular disease. However, there is limited evidence on the association between height and lipid profiles. We aimed to examine the association of height with total cholesterol and hypercholesterolemia based on the nationally representative dataset of Korean adults.
methodsThe data of 13,701 adults aged ≥19 years who participated in the Korea National Health and Nutrition Examination Survey (2013-2015) were used in this nationwide population-based cross-sectional study. Hypercholesterolemia was defined as a serum total cholesterol level ≥ 240 mg/dL or use of lipid-lowering medications. Multivariable linear regression and logistic regression analyses were used to examine the association of height with mean total cholesterol level and odds ratios (ORs) of hypercholesterolemia.
resultsApproximately 17% of participants had hypercholesterolemia. Mean total cholesterol levels decreased in the higher quartile (Q) groups of height after adjusting for confounding variables including age, sex, body mass index, smoking status, alcohol consumption, physical activity, income, educational level, hypertension, and diabetes mellitus (P for trend = 0.035). After adjusting for these potential confounding variables, the adjusted ORs of hypercholesterolemia were significantly lower in the Q3 and Q4 groups than in the Q1 group; ORs decreased in the higher quartile groups of height (OR: 0.83, 95% confidence interval: 0.71-0.99 in Q3; 0.81, 0.69-0.95 in Q4, P for trend = 0.007). The association between height (Q4 vs. Q1-Q3) and hypercholesterolemia was stronger in men or individuals without hypertension or diabetes than in women or individuals with such diseases.
conclusionsHeight is inversely associated with total cholesterol level and odds of hypercholesterolemia among Korean adults. Childhood environment related to short stature may be associated with hypercholesterolemia and cardiovascular health in adulthood.
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