Evidence map›Paper›PMID 31729960›Full record

ArticleBMC neurology2019

Classification and management of epilepsy and epileptic syndromes in a cohort of 202 school children- a 2 year follow up study- Sudan.

Inaam N Mohamed, Maha A Elseed, Somia Mohamed, Ali Alsir, Emtinan K Hamid, Ilham M Omer, Sara M Elsadig, Yasmin M Gerais, Abdelgadir H Osman, Aisha M Bakhiet and 1 more

Open access · goldAbstract read
In one paragraph

Article in BMC neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Inaam N MohamedNeurology Division, Department of pediatrics and Child Health Faculty of Medicine, University of Khartoum, P. O. Box 102, Khartoum, Sudan. inaamgashey@gmail.com.
Maha A ElseedNeurology Division, Department of pediatrics and Child Health Faculty of Medicine, University of Khartoum, P. O. Box 102, Khartoum, Sudan.
Somia MohamedNeurology Unit, Gafer Ibn Auf Specialized Hospital for Children, Khartoum, Sudan.
Ali AlsirNeurology Unit, Soba University Hospital, Khartoum, Sudan.
Emtinan K HamidDepartment of community, Faculty of Medicine, University of Khartoum, Khartoum, Sudan.
Ilham M OmerNeurology Division, Department of pediatrics and Child Health Faculty of Medicine, University of Khartoum, P. O. Box 102, Khartoum, Sudan.
Sara M ElsadigDepartment of Medicine, Faculty of Medicine, University of Khartoum, Khartoum, Sudan.
Yasmin M GeraisMinistry of Health, Khartoum, Sudan.
Abdelgadir H OsmanDepartment of Psychiatry, Faculty of Medicine, University of Khartoum, Khartoum, Sudan.
Aisha M BakhietDepartment of Psychiatry, Faculty of Medicine, University of Khartoum, Khartoum, Sudan.
Ahlam A HamedNeurology Division, Department of pediatrics and Child Health Faculty of Medicine, University of Khartoum, P. O. Box 102, Khartoum, Sudan.
University of Khartoum · SDFederal Ministry of Health · SD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn this paper, seizure types, and epilepsy syndromes are elucidated as per ILAE (2010) classification. A brief outline of the antiepileptic drug regimens used and the outcome of seizure control in a two -year period is presented. The applicability of the ILAE classification in resource limited countries has been revisited.

methodsThis is a descriptive prospective study, in which 202 patients were enrolled. The Cohort group was seen and evaluated by a pediatric neurologist at the Pediatric neurology Outpatients Department (OPD). Epilepsy was classified using the International League Against Epilepsy (ILAE) classification (2005-2009) report. All patients had an Electroencephalogram (EEG) at the start of the study, and this was repeated as deemed appropriate. Brain imaging (MRI) was done to patients when indicated. Treatment decisions were made by pediatric neurologists. Outcomes were categorized into four groups: fully recovered, well controlled, partially controlled and uncontrolled.

resultsThe mean age is 10.5 + 2.7 years. Male to female ratio was 1.7: 1. Thirty five (17.3%) patients had generalized onset seizures, 46(22.8%) had focal onset seizures, 104(51.5%) had a specific epilepsy syndrome, and 17(8.4%) patients were unclassified. 170 (84.2%) patients were on mono-therapy on their initial visit, 30(14.8%) were on two Antiepileptic Drugs (AEDs) while two (1.0%) patients were on poly-therapy. After 2 years; 155(76.7%) patients were on mono-therapy, 36(17.8%) on two AEDs while ten were (4.0%) on polytherapy. One eighty (88.2%) patients were controlled. Fifteen (7.4%) of them were off medication after being seizure free for 2 years. Twenty (9.8%) have partial control, while two (1.0%) patients were uncontrolled. Patients with focal epilepsy, those on polytherapy and those with abnormal imaging had poor prognosis.

conclusionsThe ILAE classification can be used in resource limited countries. Childhood epilepsies have a good prognosis provided they are well classified and treated.

Indexed as

AdolescentAnticonvulsantsChildCohort StudiesElectroencephalographyEpilepsyFemaleFollow-Up StudiesHumansMaleProspective StudiesSudanAnticonvulsantsClassificationEpilepsyFollow upManagementSudan

Identifiers

PMID31729960
PMCPMC6857133
OpenAlexW2984893357

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.