Trial reportSubstance abuse2021
Psychological and endocannabinoid responses to aerobic exercise in substance use disorder patients.
Trial report in Substance abuse, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02570360 (Comparative Effects of Exercise and Treatment-as-usual on Abstinence, Craving, and the Endocannabinoid System in Substance Users), which is not on this map. Cited by 24 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comparative Effects of Exercise and Treatment-as-usual on Abstinence, Craving, and the Endocannabinoid System in Substance Users
Who cites it
24 citing papers in PubMed, 6 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- Comparative effects of different types of exercise interventions on addictive craving, negative affect, and cognitive function in substance use disorder: a substance-subgroup stratified network meta-analysis.Frontiers in psychiatry · 2026Pooled it
- Effects of different exercise types on craving in substance use disorder patients with drug dependence -network meta-analysis and dose-response relationships based on frequentist and Bayesian models.Addiction science & clinical practice · 2025Pooled it
- Effect of physical exercise on the emotional and cognitive levels of patients with substance use disorder: a meta-analysis.Frontiers in psychology · 2024Pooled it
- Do Endocannabinoids Cause the Runner's High? Evidence and Open Questions.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2023Pooled it
- Effects of exercise of different intensities on withdrawal symptoms among people with substance use disorder: a systematic review and meta-analysis.Frontiers in physiology · 2023Pooled it
- A Systematic Review and Meta-Analysis on the Effects of Exercise on the Endocannabinoid System.Cannabis and cannabinoid research · 2022Pooled it
- Effects of an internet-based combined exercise and cognitive-behavioral therapy intervention on endocannabinoid system biomarkers and physical fitness in adults with mild-to-moderate depression: a SONRIE randomized controlled trial.European archives of psychiatry and clinical neuroscience · 2026Trial
- Contributions of yoga and aerobic exercise to acute changes in state affect, circulating BDNF and eCB concentrations, and memory.Psychoneuroendocrinology · 2026Trial
- Effects of Acute Exercise on Affect, Anxiety, and Self-Esteem in Poly-Substance Dependent Inpatients.European addiction research · 2023Trial
- The Endocannabinoid System in Neuropsychiatric Disorders: Mechanisms, Dysregulation and Therapeutic Potential.Biomedicines · 2026Review
- Associations of cardiorespiratory fitness and muscular fitness with plasma levels of endocannabinoids and their analogues in adults with diagnosed depression: SONRIE study.European archives of psychiatry and clinical neuroscience · 2026Article
- Aerobic exercise for substance use disorders: therapeutic effects and underlying mechanisms.Frontiers in medicine · 2026Review
- Investigating endocannabinoid system and subjective responses to exercise in cancer patients: Rationale and future research directions.JSAMS plus · 2024Review
- Review
- Acute and Long-Term Effects of App-Delivered Heartfulness Meditation on Psychological Outcomes and the Endocannabinoid Signaling System in Cyclic Vomiting Syndrome.Clinical and translational gastroenterology · 2024Article
- Exercise as Treatment for "Stress-Related" Mental Disorders.Current neuropharmacology · 2024Article
- Exercise and Acute Affect.Current topics in behavioral neurosciences · 2024Article
- The thalamic clustering coefficient moderates the vigor-sleep quality relationship.Sleep and biological rhythms · 2023Article
- The Role of Physical Exercise in Opioid Substitution Therapy: Mechanisms of Sequential Effects.International journal of molecular sciences · 2023Review
- Circulating endocannabinoids and psychological outcomes in women with PTSD.Journal of anxiety disorders · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundExercise has been examined as an adjunctive treatment for substance use disorders (SUDs), yet few exercise interventions have been conducted among patients undergoing intensive outpatient (IOP) treatment, who may be the most vulnerable to relapse and for whom exercise could provide the most benefits. This study examined the effects of aerobic exercise, in addition to IOP treatment, on psychological variables and endocannabinoids in individuals with SUDs.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.