Evidence map›Paper›PMID 31729682›Full record

ArticleMycopathologia2019

Hypercalcemia Heralding Pneumocystis jirovecii Pneumonia in an HIV-Seronegative Patient with Diffuse Cutaneous Systemic Sclerosis.

Quentin Binet, Jacques Mairesse, Marie Vanthuyne, Jean-Christophe Marot, Grégoire Wieers

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Mycopathologia, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Quentin BinetDivision of General Internal Medicine and Infectiology, Clinique St-Pierre Ottignies, Avenue Reine Fabiola, 9, 1340, Ottignies, Belgium. quentin.binet@uclouvain.be.ORCID http://orcid.org/0000-0003-3299-2385
Jacques MairesseDivision of Clinical Biology and Cytology, Clinique St-Pierre Ottignies, Ottignies, Belgium.
Marie VanthuyneDivision of Rheumatology, Cliniques Universitaires Saint-Luc, Bruxelles, Belgium.
Jean-Christophe MarotDivision of General Internal Medicine and Infectiology, Clinique St-Pierre Ottignies, Avenue Reine Fabiola, 9, 1340, Ottignies, Belgium.
Grégoire WieersDivision of General Internal Medicine and Infectiology, Clinique St-Pierre Ottignies, Avenue Reine Fabiola, 9, 1340, Ottignies, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pneumocystis pneumonia (PCP) is a life-threatening fungal infection occurring in immunocompromised patients such as HIV-positive patients with low CD4 cell count or patients under heavy immunosuppressive therapy. We report the case of a 59-year-old male with severe diffuse cutaneous systemic sclerosis presenting with asthenia, dry cough and worsening shortness of breath for the last 15 days. Biological studies were remarkable for PTH-independent severe hypercalcemia with low 25-hydroxyvitamin D and a paradoxically elevated 1,25-dihydroxyvitamin D. Early bronchoalveolar lavage allowed for PCP diagnosis and targeted treatment. We discuss the underlying physiopathology and difficulties regarding prophylaxis and treatment.

Indexed as

Pneumocystis cariniiPneumonia, PneumocystisHumansHypercalcemiaImmunocompromised HostImmunotherapyMaleMiddle AgedOpportunistic InfectionsScleroderma, DiffuseTrimethoprim, Sulfamethoxazole Drug CombinationTrimethoprim, Sulfamethoxazole Drug CombinationHypercalcemiaImmunocompromisedPneumocystis pneumoniaSystemic sclerosis

Identifiers

PMID31729682

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.