Evidence map›Paper›PMID 31729679›Full record

ArticleClinical rheumatology2020

Exposure to ambient air pollution and autoantibody status in rheumatoid arthritis.

Asha M Alex, Gary Kunkel, Harlan Sayles, Jorge D Flautero Arcos, Ted R Mikuls, Gail S Kerr

Abstract read
PubMed Publisher
In one paragraph

Article in Clinical rheumatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  12. Article
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  15. Article
  16. Review
  17. Epidemiology and Risk Factors for Rheumatoid Arthritis Development.Mediterranean journal of rheumatology · 2023
    Review
  18. Article
  19. Article
  20. Air Pollution: Another Threat to HDL Function.International journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Asha M AlexRheumatology, MedStar Georgetown University Hospital, 3800 Reservoir St NW, 3PHC, Suite, Washington, DC, 20007, USA.
Gary KunkelRheumatology, Clinic 2, University of Utah Hospital, Salt Lake City, UT, 84132, USA.
Harlan SaylesDepartment of Biostatistics, University of Nebraska Medical Center, 984375, Omaha, NE, 68198-4375, USA.
Jorge D Flautero ArcosRheumatology, DC VA Medical Center, 50 Irving St, NW, Suite 151K, Washington, DC, 20422, USA.
Ted R MikulsDepartment of Biostatistics, University of Nebraska Medical Center, 984375, Omaha, NE, 68198-4375, USA.
Gail S KerrRheumatology, MedStar Georgetown University Hospital, 3800 Reservoir St NW, 3PHC, Suite, Washington, DC, 20007, USA. gail.kerr@va.gov.ORCID http://orcid.org/0000-0002-4930-3235

Funding

HSR&D Career Development Award CDA 07-221
6 · The paper itself

Abstract

objectiveTo evaluate the relationship between air pollutant (AP) exposure and rheumatoid arthritis (RA) autoantibody status

methodsWe performed a cross sectional study utilizing enrollment data from participants in the Veterans Affairs rheumatoid arthritis registry. HLA-DRB1 shared epitope (SE), smoking, rheumatoid factor (RF), and anti-cyclic citrullinated peptide antibody (ACPA) status were collected. Mean exposure levels were obtained for AP (NO

resultsThe cohort included 557 veterans (90% male, 76% Caucasian), with mean age of 70 years and mean disease duration of 13 years. The majority were HLA-DRB1 SE, RF, and ACPA positive (73%, 79%, and 76%, respectively). In univariate models, PM

conclusionsIn an elderly cohort of RA patients, fine particulate matter (PM

Indexed as

Environmental ExposureSmokingAgedAged, 80 and overAir PollutionAllelesArthritis, RheumatoidAutoantibodiesCohort StudiesCross-Sectional StudiesEpitopesFemaleHLA-DRB1 ChainsHumansMaleMiddle AgedAutoantibodiesEpitopesHLA-DRB1 ChainsParticulate MatterRheumatoid FactorAir pollutionAutoantibodiesEnvironmentRheumatoid arthritis

Identifiers

PMID31729679

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.