Evidence map›Paper›PMID 31729523›Full record

ArticleArchives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists2021

Depression and the Diagnosis of MCI in a Culturally Diverse Sample in the United States.

Merike Lang, Mónica Rosselli, Maria T Greig, Valeria L Torres, Idaly Vélez-Uribe, Fernanda Arruda, Warren W Barker, Patricia Garcia, David A Loewenstein, Rosie E Curiel and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Merike LangDepartment of Psychology, Florida Atlantic University, Davie, FL, USA.
Mónica RosselliDepartment of Psychology, Florida Atlantic University, Davie, FL, USA.
Maria T GreigFlorida Alzheimer's Disease Research Center, Miami Beach, FL, USA.
Valeria L TorresDepartment of Psychology, Florida Atlantic University, Davie, FL, USA.
Idaly Vélez-UribeDepartment of Psychology, Florida Atlantic University, Davie, FL, USA.
Fernanda ArrudaDepartment of Psychology, Florida Atlantic University, Davie, FL, USA.
Warren W BarkerFlorida Alzheimer's Disease Research Center, Miami Beach, FL, USA.
Patricia GarciaFlorida Alzheimer's Disease Research Center, Miami Beach, FL, USA.
David A LoewensteinFlorida Alzheimer's Disease Research Center, Miami Beach, FL, USA.
Rosie E CurielFlorida Alzheimer's Disease Research Center, Miami Beach, FL, USA.
Ranjan DuaraFlorida Alzheimer's Disease Research Center, Miami Beach, FL, USA.
Florida Atlantic University · USMount Sinai Medical Center · USUniversity of Miami · US

Funding

Precision-based Assessment for the Detection of Mild Cognitive Impairment in Older AdultsR01AG055638 · NIA · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI CURIEL CID, ROSIE E · 2018 to 2022
$2.9M
Novel Detection of Early Cognitive and Functional Impairment in the ElderlyR01AG047649 · NIA · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI LOEWENSTEIN, DAVID · 2015 to 2019
$2.7M
NIA NIH HHS L30 AG060558NIA NIH HHS R01 AG047649NIA NIH HHS R01 AG055638
6 · The paper itself

Abstract

objectiveTo analyze (1) whether there are ethnic differences in the severity of depressive symptoms between groups of elders classified as cognitively normal (CN) or amnestic mild cognitive impairment (aMCI) and (2) the influence of depressive symptoms on specific cognitive performance by ethnicity across diagnoses, controlling for covariates.

methods164 Hispanics residing in the United States (HAs) and European Americans (EAs) (100 women; Mage = 72.1, SD = 8.0) were diagnosed as either CN or aMCI. Depressive symptoms were measured with the Geriatric Depression Scale (GDS-15). Cognition was assessed using the Loewenstein-Acevedo Scales for Semantic Interference and Learning (semantic memory), Multilingual Naming Test (confrontation naming), and the Stroop Test (Color-Word condition; executive function). A 2 × 2 univariate ANCOVA as well as linear and logistic regressions explored differences in depressive symptoms among diagnostic and ethnic groups.

resultsHigher depression was seen in aMCI compared to the CN group for both ethnicities, after controlling for age, education, gender, and Mini-Mental State Examination score. Greater levels of depression also predicted lower scores in confrontation naming and semantic memory for only the EA group and marginally in scores of executive function for HA participants. GDS-15 scores of ≤ 4 also predicted less likelihood of aMCI diagnosis.

conclusionsSeverity of depressive symptoms was associated with greater cognitive impairment, independent of ethnicity. Significant results suggest detrimental effects of depression on clinical diagnoses most evidently for subjects from the EA group.

Indexed as

Cognitive DysfunctionDepressionAgedCognitionExecutive FunctionFemaleHumansNeuropsychological TestsUnited StatesAgingAlzheimer’s diseaseCognitionDepressionEuropean AmericanHispanic/LatinosMemoryMild cognitive impairment

Identifiers

PMID31729523
PMCPMC7881973
OpenAlexW2989439134

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.