ArticleScientific reports2019
Sucrose intake lowers μ-opioid and dopamine D2/3 receptor availability in porcine brain.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 38 citations in OpenAlex.
- Neurobiological Consequences of High-Fat High-Sugar Diets on the Mesocorticolimbic System: a Narrative Review.Current nutrition reports · 2026Review
- Review
- Malnutrition in Substance Use Disorders: A Critical Issue in Their Treatment and Recovery.Healthcare (Basel, Switzerland) · 2025Review
- Abstinence-based treatment of comorbid eating disorders and ultra-processed food addiction.Frontiers in psychiatry · 2025Article
- Opposing effects of sugar-free claims on perceived healthiness and sweetness reduce consumers' willingness to pay for sugar-free products.Frontiers in nutrition · 2025Article
- Validation of drug-nondrug choice procedure to model maladaptive behavioural allocation to opioid use in rats.Addiction biology · 2024Article
- Total-body imaging of mu-opioid receptors with [European journal of nuclear medicine and molecular imaging · 2024Article
- Dietary intake in children and adolescents with food addiction: A systematic review.Addictive behaviors reports · 2024Review
- Astrocyte activities in the external globus pallidus regulate action-selection strategies in reward-seeking behaviors.Science advances · 2023Article
- Dopamine DNeurochemical research · 2023Article
- Ketogenic diet: a potential adjunctive treatment for substance use disorders.Frontiers in nutrition · 2023Review
- Oral oxycodone self-administration leads to features of opioid misuse in male and female mice.Addiction biology · 2023Article
- NRM 2021 Abstract Booklet.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021Article
- Drinking and smoking polygenic risk is associated with childhood and early-adulthood psychiatric and behavioral traits independently of substance use and psychiatric genetic risk.Translational psychiatry · 2021Article
- Cerebral μ-opioid and CBTranslational psychiatry · 2021Article
- The Role of Mu-Opioids for Reward and Threat Processing in Humans: Bridging the Gap from Preclinical to Clinical Opioid Drug Studies.Current addiction reports · 2021Review
- Western diet, obesity and bariatric surgery sequentially modulated anxiety, eating patterns and brain responses to sucrose in adult Yucatan minipigs.Scientific reports · 2020Article
- Type of Anaesthetic Influences [Molecular imaging and biology · 2020Article
- Fetal Programming by Methyl Donors Modulates Central Inflammation and Prevents Food Addiction-Like Behavior in Rats.Frontiers in neuroscience · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Excessive sucrose consumption elicits addiction-like craving that may underpin the obesity epidemic. Opioids and dopamine mediate the rewarding effects of drugs of abuse, and of natural rewards from stimuli such as palatable food. We investigated the effects of sucrose using PET imaging with [
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.