ArticleNature communications2019
Stroke among cancer patients.
Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 114 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
114 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Antithrombotic therapy for secondary stroke prevention in patients with cancer: a systematic review and network meta-analysis.European journal of clinical pharmacology · 2025Pooled it
- Cardiovascular mortality in people with cancer compared to the general population: A systematic review and meta-analysis.Cancer medicine · 2024Pooled it
- Is stroke incidence increased in survivors of adult cancers? A systematic review and meta-analysis.Journal of cancer survivorship : research and practice · 2022Pooled it
- A 25 year nationwide analysis of mortality trends from cerebrovascular diseases in patients with lung cancer (1999-2023).Annals of medicine and surgery (2012) · 2026Article
- Obstacles and Trials in Treating Primary Brain Tumors.International journal of molecular sciences · 2026Review
- Temporal Trends in Cause-Specific Cardiovascular Disease Mortality Following Cancer Diagnosis.Cancer medicine · 2026Article
- Recanalization therapy in stroke patients with malignancies: in-hospital outcomes by cancer subtype in a nationwide administrative data analysis.Journal of neurology · 2026Article
- Altered gut microbiota and short-chain fatty acid in acute ischaemic stroke with active cancer.Stroke and vascular neurology · 2026Observational
- Association of a Cancer Diagnosis and Mortality After Ischemic and Hemorrhagic Stroke and Myocardial Infarction.Neurology · 2026Article
- Construction of an explainable machine learning model based on SHAP for predicting cardiovascular mortality risk among American cancer survivors.Discover oncology · 2026Article
- A Robust ConvNeXt-Based Framework for Efficient, Generalizable, and Explainable Brain Tumor Classification on MRI.Bioengineering (Basel, Switzerland) · 2026Article
- Non-cardiac and cardiac risk for ischemic stroke in young adults: The Stanford Y-CORE (Young Cardiovascular Outcomes and Risk Evaluation) study.International journal of stroke : official journal of the International Stroke Society · 2026Article
- Predicting cancer aetiology in patients with stroke using brain imaging alone.BMJ neurology open · 2026Article
- Real-world safety and clinical outcomes of apixaban in patients with cancer and atrial fibrillation.Frontiers in cardiovascular medicine · 2026Article
- Tissue factor activity and 1-year mortality in patients with active cancer and acute ischemic stroke: findings from the SCAN study.Research and practice in thrombosis and haemostasis · 2026Article
- The Impact of Growth Hormone Deficiency on Endothelial Function in Childhood Brain Cancer Survivors.Cancers · 2025Article
- The B-SCancers · 2025Article
- Risk classification for non-cancer death in middle-aged cancer patients.Journal of advanced research · 2025Article
- Long-Term Outcomes and Predictors in Cancer-Related Stroke Using the Linked Data Set.Journal of the American Heart Association · 2025Article
- Specific Cardiovascular Mortality in Cancer Survivors: A Nationwide Population-Based Cohort Study in Japan.Journal of the American Heart Association · 2025Article
54 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We identify cancer patients at highest risk of fatal stroke. This is a population-based study using nationally representative data from the Surveillance, Epidemiology, and End Results program, 1992-2015. Among 7,529,481 cancer patients, 80,513 died of fatal stroke (with 262,461 person-years at risk); the rate of fatal stroke was 21.64 per 100,000-person years, and the standardized mortality ratio (SMR) of fatal stroke was 2.17 (95% CI, 2.15, 2.19). Patients with cancer of the prostate, breast, and colorectum contribute to the plurality of cancer patients dying of fatal stroke. Brain and gastrointestinal cancer patients had the highest SMRs (>2-5) through the follow up period. Among those diagnosed at <40 years of age, the plurality of strokes occurs in patients treated for brain tumors and lymphomas; if >40, from cancers of the prostate, breast, and colorectum. For almost all cancers survivors, the risk of stroke increases with time.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.