Evidence map›Paper›PMID 31729315›Full record

ArticleeLife2019

Risk factors for asthma among schoolchildren who participated in a case-control study in urban Uganda.

Harriet Mpairwe, Milly Namutebi, Gyaviira Nkurunungi, Pius Tumwesige, Irene Nambuya, Mike Mukasa, Caroline Onen, Marble Nnaluwooza, Barbara Apule, Tonny Katongole and 6 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Asthma in African children and adolescents: Burden, barriers, and management strategies.African journal of thoracic and critical care medicine · 2026
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Evaluation of the Relationship between Fractional Exhaled Nitric Oxide (FeNO) with Indoor PMInternational journal of environmental research and public health · 2022
    Article
  10. Article
  11. Allergen skin test reactivity and asthma are inversely associated with ratios of IgG4/IgE and total IgE/allergen-specific IgE in Ugandan communities.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2021
    Article
  12. Article
  13. Article
  14. Risk factors associated with rhinitis, allergic conjunctivitis and eczema among schoolchildren in Uganda.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2021
    Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 2 countries.

Harriet MpairweMedical Research Council/Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine Uganda Research Unit, Entebbe, Uganda.ORCID 0000-0003-1199-4859
Milly NamutebiMedical Research Council/Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine Uganda Research Unit, Entebbe, Uganda.
Gyaviira NkurunungiMedical Research Council/Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine Uganda Research Unit, Entebbe, Uganda.ORCID 0000-0003-4062-9105
Pius TumwesigeMedical Research Council/Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine Uganda Research Unit, Entebbe, Uganda.
Irene NambuyaMedical Research Council/Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine Uganda Research Unit, Entebbe, Uganda.
Mike MukasaMedical Research Council/Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine Uganda Research Unit, Entebbe, Uganda.
Caroline OnenMedical Research Council/Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine Uganda Research Unit, Entebbe, Uganda.
Marble NnaluwoozaMedical Research Council/Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine Uganda Research Unit, Entebbe, Uganda.
Barbara ApuleMedical Research Council/Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine Uganda Research Unit, Entebbe, Uganda.
Tonny KatongoleMedical Research Council/Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine Uganda Research Unit, Entebbe, Uganda.
Gloria OduruMedical Research Council/Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine Uganda Research Unit, Entebbe, Uganda.
Joseph KahwaMedical Research Council/Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine Uganda Research Unit, Entebbe, Uganda.
Emily L WebbLondon School of Hygiene and Tropical Medicine, London, United Kingdom.
Lawrence LubyayiMedical Research Council/Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine Uganda Research Unit, Entebbe, Uganda.
Neil PearceLondon School of Hygiene and Tropical Medicine, London, United Kingdom.
Alison M ElliottMedical Research Council/Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine Uganda Research Unit, Entebbe, Uganda.
Uganda Virus Research Institute · UGLondon School of Hygiene & Tropical Medicine · GB

Funding

European Research Council Project grant 668954Medical Research Council MC_UU_00027/5Medical Research Council MR/R010161/1Wellcome Senior fellowship 095778Wellcome Training fellowship 102512Wellcome Trust
6 · The paper itself

Abstract

Data on asthma aetiology in Africa are scarce. We investigated the risk factors for asthma among schoolchildren (5-17 years) in urban Uganda. We conducted a case-control study, among 555 cases and 1115 controls. Asthma was diagnosed by study clinicians. The main risk factors for asthma were tertiary education for fathers (adjusted OR (95% CI); 2.32 (1.71-3.16)) and mothers (1.85 (1.38-2.48)); area of residence at birth, with children born in a small town or in the city having an increased asthma risk compared to schoolchildren born in rural areas (2.16 (1.60-2.92)) and (2.79 (1.79-4.35)), respectively; father's and mother's history of asthma; children's own allergic conditions; atopy; and cooking on gas/electricity. In conclusion, asthma was associated with a strong rural-town-city risk gradient, higher parental socio-economic status and urbanicity. This work provides the basis for future studies to identify specific environmental/lifestyle factors responsible for increasing asthma risk among children in urban areas in LMICs.

Indexed as

AdolescentAir PollutantsAllergensAsthmaCase-Control StudiesChildChild, PreschoolEducational StatusFemaleHumansLife StyleMaleParentsRisk FactorsRural PopulationUgandaAir PollutantsAllergensasthmacase-control studyearly lifeepidemiologyglobal healthhumanrisk factorsschoolchildrenUganda

Identifiers

PMID31729315
PMCPMC6914334
OpenAlexW2986898709

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.