Evidence map›Paper›PMID 31729180›Full record

ArticleJournal of cellular and molecular medicine2020

Knockout of beta-2 microglobulin reduces stem cell-induced immune rejection and enhances ischaemic hindlimb repair via exosome/miR-24/Bim pathway.

Yuqing Zhang, Yanli Wang, Lianbo Shao, Xiangbin Pan, Chun Liang, Bin Liu, Yu Zhang, Wenping Xie, Bing Yan, Feng Liu and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of cellular and molecular medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 55 citations in OpenAlex.

  1. Review
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  7. Review
  8. The hope, hype and obstacles surrounding cell therapy.Journal of cellular and molecular medicine · 2024
    Review
  9. Review
  10. B2M is a Biomarker Associated With Immune Infiltration In High Altitude Pulmonary Edema.Combinatorial chemistry & high throughput screening · 2024
    Article
  11. Article
  12. Young Sca-1Journal of nanobiotechnology · 2023
    Article
  13. Review
  14. Review
  15. Article
  16. Engineering Cell Lines for Specific Human Leukocyte Antigen Presentation.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Yuqing ZhangInstitute for Cardiovascular Science & Department of Cardiovascular Surgery, First Affiliated Hospital of Soochow University, Suzhou, China.ORCID 0000-0002-4573-0192
Yanli WangInstitute for Cardiovascular Science & Department of Cardiovascular Surgery, First Affiliated Hospital of Soochow University, Suzhou, China.ORCID 0000-0002-2119-8971
Lianbo ShaoInstitute for Cardiovascular Science & Department of Cardiovascular Surgery, First Affiliated Hospital of Soochow University, Suzhou, China.ORCID 0000-0001-9322-9581
Xiangbin PanDepartment of Cardiac Surgery, Fuwai Hospital, Beijing, China.ORCID 0000-0002-2252-3393
Chun LiangDepartment of Cardiology, Shanghai Changzheng Hospital, Second Military Medical University, Shanghai, China.ORCID 0000-0002-4042-206X
Bin LiuDepartment of Cardiology, Second Hospital of Jilin University, Jilin, China.ORCID 0000-0003-2017-2160
Yu ZhangInstitute for Cardiovascular Science & Department of Cardiovascular Surgery, First Affiliated Hospital of Soochow University, Suzhou, China.ORCID 0000-0003-2101-3014
Wenping XieInstitute for Cardiovascular Science & Department of Cardiovascular Surgery, First Affiliated Hospital of Soochow University, Suzhou, China.ORCID 0000-0002-3286-7704
Bing YanInstitute for Cardiovascular Science & Department of Cardiovascular Surgery, First Affiliated Hospital of Soochow University, Suzhou, China.ORCID 0000-0003-1404-041X
Feng LiuInstitute for Cardiovascular Science & Department of Cardiovascular Surgery, First Affiliated Hospital of Soochow University, Suzhou, China.ORCID 0000-0002-0059-2152
Xi-Yong YuGuangzhou Medical University, Guangzhou, China.ORCID 0000-0003-4988-7338
Yangxin LiInstitute for Cardiovascular Science & Department of Cardiovascular Surgery, First Affiliated Hospital of Soochow University, Suzhou, China.ORCID 0000-0002-2364-3207
Soochow University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNGuangzhou Medical University · CNSecond Affiliated Hospital of Jilin University · CNSecond Military Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Generating universal human umbilical mesenchymal stem cells (UMSCs) without immune rejection is desirable for clinical application. Here we developed an innovative strategy using CRISPR/Cas9 to generate B2M

Indexed as

AnimalsBcl-2-Like Protein 11beta 2-MicroglobulinExosomesHindlimbHumansIschemiaMaleMiceMice, Inbred C57BLMice, KnockoutMicroRNAsStem CellsStem Cell TransplantationUmbilical CordBcl-2-Like Protein 11beta 2-MicroglobulinMicroRNAsMIRN24 microRNA, humanexosomeimmune rejectionischaemic hindlimb repairmesenchymal stem cellmiRNAsurvival

Identifiers

PMID31729180
PMCPMC6933348
OpenAlexW2984907234

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.