ArticleGeroScience2019
The effects of cardiorespiratory fitness on executive function and prefrontal oxygenation in older adults.
Article in GeroScience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
46 citing papers in PubMed, 56 citations in OpenAlex.
- Synergistic effects of tDCS combined with aerobic exercise on pulmonary function and heart rate in sedentary young people.Scientific reports · 2025Trial
- Trial
- Mild exercise improves executive function with increasing neural efficiency in the prefrontal cortex of older adults.GeroScience · 2024Trial
- Reliability of Behavioral and fNIRS Neural Responses: Assessments During Posture-Inhibitory Control Dual Tasking.NeuroSci · 2026Article
- Lower-limb physical function is associated with executive function in frail older adults.GeroScience · 2026Article
- Association between 24-h activity patterns and inhibitory control in community-dwelling older adults: a cross-sectional study based on chronic disease status.Frontiers in public health · 2026Article
- Can aerobic exercise really improve factors related to decision-making capacity in aging? What has been measured, what has been assumed, and what needs to change.Frontiers in sports and active living · 2026Review
- Cardiorespiratory fitness and cardiometabolic health are associated with distinct cognitive domains in cognitively healthy older adults.Scientific reports · 2025Article
- The relationship between grip strength, 6 minute walking distance and working memory in older adults with mild cognitive impairment: an fNIRS study.BMC geriatrics · 2025Article
- Effects of aerobic exercise on memory functions and serum levels of BDNF and TrkB in young adult and older adult male football players.Journal of exercise science and fitness · 2025Article
- The Influence of Workplace-Integrated Exercise Snacks on Cognitive Performance in Sedentary Middle-Aged Adults-A Randomized Pilot Study.Sports (Basel, Switzerland) · 2025Article
- Cardiorespiratory fitness is associated with cognitive function in late adulthood: baseline findings from the IGNITE study.British journal of sports medicine · 2025Article
- Cerebral oxygenation during submaximal and peak exercise for sedentary adults with and without down syndrome.Frontiers in physiology · 2025Article
- The examination of physical function and cognitive outcomes in middle-to-older high-risk adults: an unsupervised clustering method.Frontiers in public health · 2025Article
- Association between physical fitness and executive functions in cognitively healthy female older adults: a cross-sectional study.GeroScience · 2024Article
- Cardiorespiratory fitness is associated with cognitive performance in 80 + -year-olds: Detangling processing levels.GeroScience · 2024Article
- Association between changes in habitual stepping activity and cognition in older adults.Scientific reports · 2024Article
- Frailty is associated with worse executive function and higher cerebral blood velocity in cognitively healthy older adults: a cross-sectional study.GeroScience · 2024Article
- Moderate intensity intermittent lifestyle physical activity is associated with better executive function in older adults.Frontiers in sports and active living · 2024Article
- Comparative effects of open-skill and closed-skill sports on executive function in university students: a 16-week quasi-experimental study.Frontiers in psychology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Reviews on cardiovascular fitness and cognition in older adults suggest that a higher level of cardiorespiratory fitness may protect the brain against the effects of aging. Although studies reveal positive effects of cardiorespiratory fitness on executive function, more research is needed to clarify the underlying mechanisms of these effects in older adults. The aim of the current study was to assess the association between cardiorespiratory fitness level, cerebral oxygenation, and cognitive performance in older adults (OAs). Seventy-four OAs (68 ± 6.3 years) gave their written, informed consent to participate in the study. Complete data was collected from 66 participants. All participants underwent a cycle ergometer maximal continuous graded exercise test in order to assess their peak power output (PPO) and a neuropsychological paper and pencil tests (Trail Making Test A and B) while changes in left prefrontal cortex oxygenation were measured with functional near-infrared spectroscopy (fNIRS). The results reveal increased cardiorespiratory fitness was associated with decreased response time (i.e., better performance) on the Trail Making Test (B) (standardized β = - 0.42, p < 0.05). Cerebral oxygenation in higher fit older adults mediated the relationship with improved executive functioning (standardized β = - 0.08, p < 0.05). Specifically, in older adults with higher cardiorespiratory fitness (based on a median split), cerebral oxygenation was related to executive functioning but no such relationship existed in lower fit adults.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.