Evidence map›Paper›PMID 31728874›Full record

ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2020

Is paroxysmal supraventricular tachycardia truly benign? Insightful association between PSVT and stroke from a National Inpatient Database Study.

Sharan Prakash Sharma, Ashok Kondur, Rakesh Gopinathannair, Timothy Kamerzell, Moussa Mansour, Srijoy Mahapatra, Krzysztof Bartus, Dhanunjaya Lakkireddy

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In one paragraph

Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 2 countries.

Sharan Prakash SharmaDivision of Cardiovascular Medicine, Garden City Hospital, Garden City, MI, USA.
Ashok KondurDivision of Cardiovascular Medicine, Garden City Hospital, Garden City, MI, USA.
Rakesh GopinathannairThe Kansas City Heart Rhythm Institute, HCA MidWest Health, 12200 West 106th Street, Suite 320, Overland Park, KS, Overland Park, KS, 661215, USA.
Timothy KamerzellQuivira Internal Medicine, Overland Park Regional Medical Center, Overland Park, KS, USA.
Moussa MansourSection of Electrophysiology, Massachusetts General Hospital, Boston, MA, USA.
Srijoy MahapatraAbbott Laboratories, Minneapolis, MN, USA.
Krzysztof BartusDepartment of Cardiovascular Surgery and Transplantology, Jagiellonian University Medical College, John Paul II Hospital, Krakow, Poland.
Dhanunjaya LakkireddyThe Kansas City Heart Rhythm Institute, HCA MidWest Health, 12200 West 106th Street, Suite 320, Overland Park, KS, Overland Park, KS, 661215, USA. dhanunjaya.lakkireddy@hcahealthcare.com.
Garden City Community College · USWest Health · USAbbott (United States) · USJohn Paul II Hospital · PLMassachusetts General Hospital · USRegional Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAtrial fibrillation and flutter are well-known causes of stroke. Whether other atrial arrhythmias categorized as paroxysmal supraventricular tachycardia (PSVT) are associated with stroke is less clear. We aimed to evaluate the association of PSVT with ischemic and embolic stroke and its impact on short-term outcomes in hospitalized stroke patients.

methodsNational Inpatient Sample database of the USA was used to assess the association of PSVT with ischemic stroke. Atrial fibrillation and flutter were excluded to minimize the confounding effects. The association of PSVT with stroke was evaluated using univariate and multivariate analysis. Subgroup analyses by gender, age, and stroke type were also performed.

resultsPSVT was associated with increased odds of overall ischemic stroke in univariate [OR 1.18 (95% CI 1.09-1.27) p < 0.001] analysis. No such association was observed in multivariate analysis (OR 1.06 (95% CI 0.98-1.14) p = 0.1) or with subgroup analysis by gender and age. However, PSVT was associated with embolic stroke in both univariate (OR 2.01 (95%CI 1.67-2.43, p < 0.001) and multivariate analysis (OR 1.7 (95%CI 1.4-2.14) p < 0.001) as well as in subgroup analyses by gender and age. Furthermore, the presence of PSVT was associated with increased mortality in embolic stroke (OR 4.11, CI 2.29 to 7.39, p < 0.001) and increased total hospital cost and length of hospital stay in all stroke types.

conclusionsPSVT is independently associated with higher prevalence of embolic stroke but not with overall ischemic stroke. Patients with embolic stroke in the presence of PSVT have worse in-hospital outcomes with increased mortality.

Indexed as

Atrial FibrillationStrokeTachycardia, ParoxysmalTachycardia, SupraventricularTachycardia, VentricularHumansInpatientsEmbolic strokeIschemic strokeNational Inpatient databaseParoxysmal supraventricular tachycardia

Identifiers

PMID31728874
OpenAlexW2985048012

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.