Evidence map›Paper›PMID 31728853›Full record

ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2020

Individualized intravenous thrombolytic strategy for acute ischemic stroke with large vessel occlusion on the era of mechanical thrombectomy: cases report.

Pengfei Xing, Hongjian Shen, Zifu Li, Pengfei Yang, Yongwei Zhang, Jianmin Liu

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

6 authors.

Pengfei XingDepartment of Cerebrovascular Disease Center, Changhai Hospital, Second Military Medical University, No.168 Changhai Rd, Shanghai, 200433, China.ORCID http://orcid.org/0000-0002-2663-1092
Hongjian ShenDepartment of Cerebrovascular Disease Center, Changhai Hospital, Second Military Medical University, No.168 Changhai Rd, Shanghai, 200433, China.
Zifu LiDepartment of Cerebrovascular Disease Center, Changhai Hospital, Second Military Medical University, No.168 Changhai Rd, Shanghai, 200433, China.
Pengfei YangDepartment of Cerebrovascular Disease Center, Changhai Hospital, Second Military Medical University, No.168 Changhai Rd, Shanghai, 200433, China.
Yongwei ZhangDepartment of Cerebrovascular Disease Center, Changhai Hospital, Second Military Medical University, No.168 Changhai Rd, Shanghai, 200433, China. zhangyongwei@163.com.
Jianmin LiuDepartment of Cerebrovascular Disease Center, Changhai Hospital, Second Military Medical University, No.168 Changhai Rd, Shanghai, 200433, China. Liu118@vip.163.com.

Funding

NCCDPHP CDC HHS GN-2017R0001
6 · The paper itself

Abstract

Intravenous thrombolysis for acute ischemic stroke within 4.5 h after the onset of symptoms has become a standard therapy that is recommended by many trials and clinical guidelines. As on the era of mechanical thrombectomy for acute ischemic stroke with large vessel occlusions, whether intravenous thrombolysis (IVT) is still necessary, and how to choose the optimal dose are still controversy. Here, we reported two cases of acute ischemic stroke with large vessel occlusions that both achieved complete recanalization after IVT. Then, IVT was terminated in advance, and dynamic surveillance by DSA was performed to achieve individual treatment. However, both of the cases presented with hemorrhagic transformation. We analyzed the probable reasons and put forward thoughts from ourselves.

Indexed as

AgedAged, 80 and overAngiography, Digital SubtractionBrain IschemiaComputed Tomography AngiographyFibrinolytic AgentsHumansInfarction, Middle Cerebral ArteryMaleStrokeFibrinolytic AgentsIntravenous thrombolysisIschemic strokeMechanical thrombectomy

Identifiers

PMID31728853
PMCPMC7039837

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.