Evidence map›Paper›PMID 31728799›Full record

ArticlePlant foods for human nutrition (Dordrecht, Netherlands)2019

Anti-Influenza Virus Activity of Adlay Tea Components.

Emiko Nagai, Miwa Iwai, Ritsuko Koketsu, Yoshinobu Okuno, Yuri Suzuki, Ryosuke Morimoto, Hidenobu Sumitani, Atsushi Ohshima, Toshiki Enomoto, Yuji Isegawa

Abstract read
PubMed Publisher
In one paragraph

Article in Plant foods for human nutrition (Dordrecht, Netherlands), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Anti-Influenza Virus Activity ofFoods (Basel, Switzerland) · 2023
    Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Juice ofFood science & nutrition · 2021
    Article
  12. Review
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Emiko NagaiDepartment of Food Science, Ishikawa Prefectural University, Nonoichi, Ishikawa, 921-8836, Japan.
Miwa IwaiDepartment of Food Sciences and Nutrition, Mukogawa Women's University, Ikebiraki, Nishinomiya, Hyogo, 663-8558, Japan.
Ritsuko KoketsuResearch Foundation for Microbial Diseases of Osaka University, Osaka University, Suita, Osaka, 565-0871, Japan.
Yoshinobu OkunoOsaka Institute of Public Health, Osaka, 537-0025, Japan.
Yuri SuzukiDepartment of Food Sciences and Nutrition, Mukogawa Women's University, Ikebiraki, Nishinomiya, Hyogo, 663-8558, Japan.
Ryosuke MorimotoDepartment of Food Sciences and Nutrition, Mukogawa Women's University, Ikebiraki, Nishinomiya, Hyogo, 663-8558, Japan.
Hidenobu SumitaniToyo Institute of Food Technology, Kawanishi, Hyogo, 666-0026, Japan.
Atsushi OhshimaGenomics Program, Nagahamabio Institute of Bio-Science and Technology, Nagahama, Shiga, 526-0829, Japan.
Toshiki EnomotoDepartment of Food Science, Ishikawa Prefectural University, Nonoichi, Ishikawa, 921-8836, Japan.
Yuji IsegawaDepartment of Food Sciences and Nutrition, Mukogawa Women's University, Ikebiraki, Nishinomiya, Hyogo, 663-8558, Japan. isegawa@mukogawa-u.ac.jp.ORCID http://orcid.org/0000-0001-9701-8431
Mukogawa Women's University · JPIshikawa Prefectural University · JPNagahama Institute of Bio-Science and Technology · JPOsaka Prefectural Institute of Public Health · JPThe University of Osaka · JPToyo Institute of Food Technology · JP

Funding

Japan Society for the Promotion of Science JP 24501017
6 · The paper itself

Abstract

Our previous study showed anti-influenza virus activity in adlay tea prepared from adlay seeds, naked barley seeds, soybean, and cassia seeds. In this study, we evaluated the anti-influenza virus activity of each component of this tea and analyzed their active ingredients. Each component was roasted and extracted in hot water; the extracts were tested for antiviral activity and their mechanisms of action were studied. All the tea components showed antiviral activity against the H1N1 and H3N2 influenza subtypes and against influenza B. The viral stages inhibited by the components were virus adsorption and replication in proliferative process, suggesting that the action mechanisms of the components might differ from those of oseltamivir acid. Of the tea components, soybean showed the strongest activity. Therefore, we analyzed its active ingredients by liquid chromatography quadruple time-of-flight mass spectrometry (LC/qTOF-MS) and daidzein and glycitein were detected as active ingredients. Here, anti-influenza virus action of glycitein was the first report.

Indexed as

Influenza A Virus, H1N1 SubtypeInfluenza, HumanHumansInfluenza A Virus, H3N2 SubtypeTeaVirus ReplicationTeaAdlayAnti-influenza virusDaidzeinGlyciteinNaked barleySoybean

Identifiers

PMID31728799
OpenAlexW2986627822

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.