Observational studyTechniques in coloproctology2019
Emergency surgery for obstructing and perforated colon cancer: patterns of recurrence and prognostic factors.
Observational study in Techniques in coloproctology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 2 of them syntheses that pooled it.
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Who cites it
39 citing papers in PubMed, 2 syntheses or guidelines pooled it, 94 citations in OpenAlex.
- Inadvertent laparoscopic lavage of perforated colon cancer: a systematic review.Langenbeck's archives of surgery · 2024Pooled it
- Perineural invasion is increased in patients receiving colonic stenting as a bridge to surgery: a systematic review and meta-analysis.Techniques in coloproctology · 2021Pooled it
- Risk of Bowel Obstruction in Patients Undergoing Neoadjuvant Chemotherapy for High-risk Colon Cancer: A Nested Case-control-matched Analysis of an International, Multicenter, Randomized Controlled Trial (FOxTROT).Annals of surgery · 2024Trial
- Emergency Diagnostic Phenotypes and Differential Survival in Colorectal Cancer: A Real-World Cohort Study.Diagnostics (Basel, Switzerland) · 2026Article
- Decision-making in emergency colorectal surgery for cancer.Annals of medicine and surgery (2012) · 2026Article
- The Prognostic Role of Postoperative Inflammation After Minimally Invasive Resection for Colorectal Cancer.Annals of surgical oncology · 2026Article
- Independent Prognostic Significance of Perforation in Colorectal Cancer: Insights From a Propensity Score-Matched Cohort Study.Annals of gastroenterological surgery · 2026Article
- Case Report: splenic abscess as a rare complication of perforated splenic flexure colorectal carcinoma: the role of imaging and multidisciplinary management.Frontiers in oncology · 2026Article
- Development of a preoperative predictive classifier and tailored staging system for obstructive colorectal cancer.BMC surgery · 2025Article
- Influencing factors and predictive model of the early postoperative recurrence of colorectal cancer with obstruction.World journal of gastrointestinal surgery · 2025Article
- Local and National Trends in Emergency Presentation of Colon and Rectal Cancer.Journal of surgical oncology · 2025Article
- Comparison of early and long-term clinical outcomes in obstructed proximal and distal colon cancers undergoing emergent surgery.Przeglad gastroenterologiczny · 2025Article
- Article
- Colonic stenting: is the bridge to surgery worth its cost? A cost-effectiveness analysis at a single Asian institution.Annals of coloproctology · 2024Article
- Exploring 6 years of colorectal cancer surgery in rural Italy: insights from 648 consecutive patients unveiling successes and challenges.Updates in surgery · 2024Article
- Palliative surgery: state of the science and future directions.The British journal of surgery · 2024Article
- Why is early detection of colon cancer still not possible in 2023?World journal of gastroenterology · 2024Review
- Construction of a predictive model for postoperative hospitalization time in colorectal cancer patients based on interpretable machine learning algorithm: a prospective preliminary study.Frontiers in oncology · 2024Article
- Quality of emergency oncological surgery: time for advanced oncological life support.Revista da Associacao Medica Brasileira (1992) · 2024Review
- Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of this study was to analyze the incidence, patterns and prognostic factors of recurrence in patients with complicated colon cancer who had emergency surgery within 24 h of admission.
methodsA retrospective observational study was performed on patients with obstructing or perforated colon cancer having resection with curative intent between 1996 and 2014 at a single center. Data were obtained from a prospectively maintained database. Patients who had rectal cancer, iatrogenic endoscopic perforation, stage IV disease, palliative surgery, a colonic stent or decompressive colostomy were excluded.
resultsThe study included 393 patients. Obstruction was observed in 320 patients (81.4%) and perforation in 73 (18.6%). Hartmann's procedure was more frequently performed by general surgeons (7.5% vs 23.3%; p = 0.023). 30-day postoperative mortality was 13.5% (53/393), including 47 (14.7%) obstructed and 6 (8.2%) perforated patients. Postoperative complications (Clavien-Dindo III-IV) occurred in 87 patients (22.1%), including 68 (21.2%) of obstructed and 19 (26.0%) of perforated patients. Anastomotic dehiscence was diagnosed in 52 of 329 (15.8%) patients with primary anastomosis and was higher in the obstructing group than in the perforated group (17.4% vs 7.6%). There was a significantly higher anastomotic dehiscence rate after procedures performed by general surgeons when compared with those performed by colorectal surgeons (10.3% vs 21.3%; p = 0.005; OR 2.81, 95% CI 1.4-5.9). With a median follow-up of 6 years, the recurrence rate was 30.1% (67.4% distant, 22.8% local, 9.8% both). Overall and cancer-related survivals were 68.7% and 77.8%, respectively. The presence of positive nodes, male gender, anastomotic dehiscence and diffuse peritonitis were independent predictors for local recurrence while type of surgeon (general) was an independent factor for distant recurrence.
conclusionsMale gender, diffuse peritonitis, positive lymph nodes, type of surgeon and postoperative anastomotic dehiscence significantly influence recurrence of colorectal cancer in this series.
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