Evidence map›Paper›PMID 31728748›Full record

ArticlePediatric nephrology (Berlin, Germany)2020

Plasma pseudouridine levels reflect body size in children on hemodialysis.

Frank J O'Brien, Tammy L Sirich, Abigail Taussig, Enrica Fung, Lakshmi L Ganesan, Natalie S Plummer, Paul Brakeman, Scott M Sutherland, Timothy W Meyer

Abstract read
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In one paragraph

Article in Pediatric nephrology (Berlin, Germany), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Frank J O'BrienDepartment of Medicine, Washington University School of Medicine, St. Louis, MO, USA.
Tammy L SirichDepartments of Medicine, VA Palo Alto HCS and Stanford University, 3801 Miranda Ave, Palo Alto, CA, 94304, USA.
Abigail TaussigDepartments of Medicine, VA Palo Alto HCS and Stanford University, 3801 Miranda Ave, Palo Alto, CA, 94304, USA.
Enrica FungLoma Linda University School of Medicine and VA Loma Linda HCS, Loma Linda, CA, USA.
Lakshmi L GanesanDepartment of Pediatrics, Stanford University, Palo Alto, CA, USA.
Natalie S PlummerDepartments of Medicine, VA Palo Alto HCS and Stanford University, 3801 Miranda Ave, Palo Alto, CA, 94304, USA.
Paul BrakemanDepartment of Pediatrics, University of California, San Francisco, CA, USA.
Scott M SutherlandDepartment of Pediatrics, Stanford University, Palo Alto, CA, USA.
Timothy W MeyerDepartments of Medicine, VA Palo Alto HCS and Stanford University, 3801 Miranda Ave, Palo Alto, CA, 94304, USA. twmeyer@stanford.edu.ORCID 0000-0001-9707-5399
Palo Alto University · USVA Palo Alto Health Care System · USLoma Linda University · USUniversity of California, San Francisco · USWashington University in St. Louis · US

Funding

Dietary and Microbial Reprogramming of Intestinal Microbiota-Produced MetabolitesR01DK101674 · NIDDK · STANFORD UNIVERSITY · PI FISCHBACH, MICHAEL ANDREW, MEYER, TIMOTHY W · 2014 to 2024
$6.5M
NIH HHS R01 DK101674VA CX-001036-01A1
6 · The paper itself

Abstract

backgroundDialysis in children as well as adults is prescribed to achieve a target spKt/V

methodsPU and urea nitrogen (ureaN) were measured in plasma and dialysate at the midweek hemodialysis session in 20 pediatric patients, with BSA ranging from 0.65-1.87m

resultsThe dialytic clearance (K

conclusionsPrescribing dialysis based on urea kinetics may leave uremic solutes at higher levels in small children. Measurement of a solute produced proportional to BSA may provide a better index of dialysis adequacy than measurement of urea.

Indexed as

Body SizeModels, TheoreticalAdolescentBiomarkersBody Surface AreaChildChild, PreschoolFemaleHumansMalePseudouridineRenal DialysisUreaYoung AdultBiomarkersPseudouridineUreaAdequacyChildrenHemodialysisUremic solutes

Identifiers

PMID31728748
OpenAlexW2983032754

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.