Evidence map›Paper›PMID 31728696›Full record

ArticleAIDS and behavior2020

Depressive Symptom Trajectories Among People Living with HIV in a Collaborative Care Program.

Douglas Gunzler, Steven Lewis, Allison Webel, Mallika Lavakumar, Diana Gurley, Katherine Kulp, McKenzie Pile, Victoria El-Hayek, Ann Avery

Open access · greenAbstract read
In one paragraph

Article in AIDS and behavior, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Douglas GunzlerCenter for Healthcare Research and Policy, Case Western Reserve University School of Medicine, 2500 Metrohealth Drive, Cleveland, OH, 44109, USA. dgunzler@metrohealth.org.ORCID http://orcid.org/0000-0003-3786-8578
Steven LewisCenter for Healthcare Research and Policy, Case Western Reserve University School of Medicine, 2500 Metrohealth Drive, Cleveland, OH, 44109, USA.
Allison WebelSchool of Nursing, Case Western Reserve University, Cleveland, OH, USA.
Mallika LavakumarDepartment of Psychiatry, MetroHealth Medical Center, Case Western Reserve University, Cleveland, OH, USA.
Diana GurleyDepartment of Psychiatry, MetroHealth Medical Center, Case Western Reserve University, Cleveland, OH, USA.
Katherine KulpMiddlebury College, Middlebury, VT, USA.
McKenzie PileWheaton College, Wheaton, IL, USA.
Victoria El-HayekDepartment of Internal Medicine, Case Western Reserve University, Cleveland, OH, USA.
Ann AveryDepartment of Internal Medicine, Case Western Reserve University, Cleveland, OH, USA.
Case Western Reserve University · USMetroHealth Medical Center · USMiddlebury College · USWheaton College - Illinois · US

Funding

Clinical and Translational Science Collaborative of ClevelandUL1TR002548 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI MCCOMSEY, GRACE A · 2018 to 2022
$35.5M
HRSA HHS H97HA27429-01-00NCATS NIH HHS UL1 TR002548
6 · The paper itself

Abstract

Depressive symptoms may differ in severity and change over time in people living with HIV (PLWH). Describing depression trajectories and associated clinical characteristics of PLWH in an interventional study may help in developing a more personalized medicine approach. Using latent class growth analysis four, 15-month self-reported depression trajectories were identified in 416 PLWH participating in a collaborative care program. The four subgroups were characterized by improving (58.4% [of participants]), worsening (9.4%), highly responsive (19.5%) and persistently severe (12.7%) depressive symptoms. A high proportion of individuals were in trajectories marked by improvement. Further, the highly responsive group had on average, over 50% reduction of self-reported depressive symptoms. Self-reported trauma, posttraumatic stress disorder, lower neighborhood-level education and fewer HIV and psychiatry clinic visits were associated with worsening or persistently severe depressive symptom trajectories. Members of the persistently severe group were less likely to be virally suppressed after 12-months. Identifying subgroups of PLWH based on changes in self-reported depressive symptoms may further inform intervention approaches that can advance care.

Indexed as

Residence CharacteristicsAdultAmbulatory Care FacilitiesDepressionDepressive DisorderFemaleHIV InfectionsHumansLatent Class AnalysisLongitudinal StudiesMaleMiddle AgedPoverty AreasPsychiatric Status Rating ScalesStress Disorders, Post-TraumaticCollaborative care modelDepressionHIV viral suppressionLatent class growth analysisLongitudinal studiesReported trauma

Identifiers

PMID31728696
PMCPMC7220833
OpenAlexW2988812407

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.