Evidence map›Paper›PMID 31728312›Full record

ArticleQuantitative imaging in medicine and surgery2019

Mehran Shaghaghi, Weiwei Chen, Alessandro Scotti, Haiqi Ye, Yan Zhang, Wenzhen Zhu, Kejia Cai

Abstract read
In one paragraph

Article in Quantitative imaging in medicine and surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Quantitative imaging in medicine and surgery · 2025
    Article
  3. Article
  4. Review
  5. Quasi-steady-state (QUASS) reconstruction enhances TMagnetic resonance in medicine · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Editorial: Imaging of neurometabolism.Frontiers in neuroscience · 2023
    Article
  12. Article
  13. TowardBiosensors · 2022
    Review
  14. CombiningFrontiers in neuroscience · 2022
    Article
  15. Article
  16. In Vivo Proton Exchange Rate (kJournal of magnetic resonance imaging : JMRI · 2021
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mehran ShaghaghiDepartment of Radiology, University of Illinois at Chicago, Chicago, IL, USA.
Weiwei ChenDepartment of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430030, China.
Alessandro ScottiDepartment of Radiology, University of Illinois at Chicago, Chicago, IL, USA.
Haiqi YeDepartment of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430030, China.
Yan ZhangDepartment of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430030, China.
Wenzhen ZhuDepartment of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430030, China.
Kejia CaiDepartment of Radiology, University of Illinois at Chicago, Chicago, IL, USA.

Funding

Deciphering molecular mechanisms that underlie brain endothelial cell dysfunction with APOE4R01AG061114 · NIA · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Leon Maing Tai · 2019 to 2026
$4.7M
Targeting APOE modulated neurovascular dysfunctionR21AG053876 · NIA · UNIVERSITY OF ILLINOIS AT CHICAGO · PI TAI, LEON MAING · 2017 to 2018
$440k
Take pictures of short-lived ROS with endogenous contrast MRIR21EB023516 · NIBIB · UNIVERSITY OF ILLINOIS AT CHICAGO · PI CAI, KEJIA · 2017 to 2018
$440k
NIA NIH HHS R01 AG061114NIA NIH HHS R21 AG053876NIBIB NIH HHS R21 EB023516
6 · The paper itself

Abstract

backgroundTo implement omega plot method for

methodsFour Z-spectra were collected with chemical exchange saturation transfer (CEST) saturation power =1, 2, 3 & 4 µT. Water DS was estimated by fitting the Z-spectrum to a linear combination of multiple Lorentzian components and its contribution to the signal was subsequently removed. Exchange rate maps were derived by the omega plot, consisting of fitting the inverse of the signal intensity,

resultsThe exchange rate values quantified with the DS removed omega plot were significantly higher in the GM region than in the WM region (616±29

conclusionsThe calculated exchange rate with DS-corrected omega plot is a weighted average for all saturation transfer exchanging proton species which contribute to Z-spectral signal. The healthy brain exchange rate map provided by DS-removed omega plots may serve as a baseline for detecting any pathological changes.

Indexed as

Chemical exchange saturation transfer (CEST)human brainOmega plotproton exchange rate

Identifiers

PMID31728312
PMCPMC6828586

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.