Evidence map›Paper›PMID 31728282›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2019

A Short Peptide Hydrogel with High Stiffness Induced by 3

Shu Hui Hiew, Harini Mohanram, Lulu Ning, Jingjing Guo, Antoni Sánchez-Ferrer, Xiangyan Shi, Konstantin Pervushin, Yuguang Mu, Raffaele Mezzenga, Ali Miserez

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Construction of ZnGels (Basel, Switzerland) · 2026
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  17. A Short Peptide Hydrogel with High Stiffness Induced by 3Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shu Hui HiewCenter for Biomimetic Sensor Science School of Materials Science and Engineering Nanyang Technological University Singapore 639798 Singapore.
Harini MohanramCenter for Biomimetic Sensor Science School of Materials Science and Engineering Nanyang Technological University Singapore 639798 Singapore.
Lulu NingSchool of Biological Sciences Nanyang Technological University Singapore 637551 Singapore.
Jingjing GuoSchool of Biological Sciences Nanyang Technological University Singapore 637551 Singapore.
Antoni Sánchez-FerrerDepartment of Health Sciences & Technology ETH Zurich Zurich CH-8092 Switzerland.
Xiangyan ShiSchool of Biological Sciences Nanyang Technological University Singapore 637551 Singapore.
Konstantin PervushinSchool of Biological Sciences Nanyang Technological University Singapore 637551 Singapore.
Yuguang MuSchool of Biological Sciences Nanyang Technological University Singapore 637551 Singapore.
Raffaele MezzengaDepartment of Health Sciences & Technology ETH Zurich Zurich CH-8092 Switzerland.
Ali MiserezCenter for Biomimetic Sensor Science School of Materials Science and Engineering Nanyang Technological University Singapore 639798 Singapore.ORCID https://orcid.org/0000-0003-0864-8170

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biological gels generally require polymeric chains that produce long-lived physical entanglements. Low molecular weight colloids offer an alternative to macromolecular gels, but often require ad-hoc synthetic procedures. Here, a short biomimetic peptide composed of eight amino acid residues derived from squid sucker ring teeth proteins is demonstrated to form hydrogel in water without any cross-linking agent or chemical modification and exhibits a stiffness on par with the stiffest peptide hydrogels. Combining solution and solid-state NMR, circular dichroism, infrared spectroscopy, and X-ray scattering, the peptide is shown to form a supramolecular, semiflexible gel assembled from unusual right-handed 3

Indexed as

molecular dynamics (MD) simulationsNMR spectroscopypeptide hydrogelssuckerinβ‐sheet transition

Identifiers

PMID31728282
PMCPMC6839752

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.