Evidence map›Paper›PMID 31728222›Full record

ArticleSultan Qaboos University medical journal2019

Impact of Comorbidities on Survival Among Patients with Chronic Myeloid Leukaemia Using the Charlson Comorbidity Index: Retrospective study from Basra, Iraq.

Rafid A Abood, Hasson M Hasson, Asaad A Khalaf, Elaf M Saleh

Abstract read
In one paragraph

Article in Sultan Qaboos University medical journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rafid A AboodDepartment of Medicine, Basra College of Medicine, Basra, Iraq.
Hasson M HassonBasra Oncology & Haematology Centre, Basra, Iraq.
Asaad A KhalafDepartment of Public Health, Basra Health Directorate, Basra, Iraq.
Elaf M SalehBasra Oncology & Haematology Centre, Basra, Iraq.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesIn chronic diseases, comorbidities are known to have a strong negative association with overall survival (OS). This study aimed to use the Charlson Comorbidity Index (CCI) to examine the effect of comorbidities on OS among patients with chronic myeloid leukaemia (CML) treated with tyrosine kinase inhibitors.

methodsThis retrospective study was conducted between January 2006 and October 2016 and included 247 CML patients treated at the Basra Oncology & Haematology Centre, Basra, Iraq. Information from hospital records was used to calculate CCI scores and patients were divided into groups based on scores of 2-3 (CCI1 group) or ≥4 (CCI2 group). The OS was calculated using Kaplan-Meier curves.

resultsThere were 177 (71.7%) patients in the CCI1 group and 70 (28.3%) in the CCI2 group. Overall, patients in the CCI1 group were significantly younger compared to those in the CCI2 group (median age: 35 versus 60 years;

conclusionNo significant correlation was found between CCI score and OS among CML patients in Basra. However, larger long-term prospective studies are needed to evaluate associations with median age at diagnosis and disease severity and to develop region-specific prognostic scales.

Indexed as

ComorbidityAdultDisease ProgressionFemaleHumansIraqLeukemia, Myelogenous, Chronic, BCR-ABL PositiveMaleMiddle AgedPrognosisRetrospective StudiesSurvival AnalysisChronic DiseasesChronic Myeloid LeukemiaComorbidityIraqMortalitySurvival Analysis

Identifiers

PMID31728222
PMCPMC6839677

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